TY - JOUR AU - Salvador-Martín, Sara AU - Raposo-Gutiérrez, Irene AU - Navas-López, Víctor Manuel AU - Gallego-Fernández, Carmen AU - Moreno-Álvarez, Ana AU - Solar-Boga, Alfonso AU - Muñoz-Codoceo, Rosana AU - Magallares, Lorena AU - Martínez-Ojinaga, Eva AU - Fobelo, María J. AU - Millán-Jiménez, Antonio AU - Rodriguez-Martinez, Alejandro AU - Vayo, Concepción A. AU - Sánchez, Cesar AU - Tolin, Mar AU - Bossacoma, Ferrán AU - Pujol-Muncunill, Gemma AU - González de Caldas, Rafael AU - Loverdos, Inés AU - Blanca-García, José A. AU - Segarra, Oscar AU - Eizaguirre, Francisco J. AU - García-Romero, Ruth AU - Merino-Bohórquez, Vicente AU - Sanjurjo-Sáez, María AU - López-Fernández, Luis A. PY - 2020 DO - 10.3390/ijms21093364 UR - http://hdl.handle.net/10668/3700 T2 - International Journal of Molecular Sciences AB - Around a 20-30% of inflammatory bowel disease (IBD) patients are diagnosed before they are 18 years old. Anti-TNF drugs can induce and maintain remission in IBD, however, up to 30% of patients do not respond. The aim of the work was to identify... LA - en PB - MDPI KW - Biomarker KW - Gene expression KW - Infliximab KW - Adalimumab KW - Ulcerative colitis KW - Crohn’s disease KW - Biomarcadores KW - Expresión génica KW - Colitis ulcerosa KW - Enfermedad de Crohn KW - Medical Subject Headings::Persons::Persons::Age Groups::Adolescent KW - Medical Subject Headings::Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Therapeutic Uses::Anti-Inflammatory Agents KW - Medical Subject Headings::Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Therapeutic Uses::Antirheumatic Agents KW - Medical Subject Headings::Persons::Persons::Age Groups::Child KW - Medical Subject Headings::Persons::Persons::Age Groups::Child::Child, Preschool KW - Medical Subject Headings::Check Tags::Female KW - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Processes::Gene Expression Regulation KW - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans KW - Medical Subject Headings::Persons::Persons::Age Groups::Infant KW - Medical Subject Headings::Diseases::Digestive System Diseases::Gastrointestinal Diseases::Intestinal Diseases::Inflammatory Bowel Diseases KW - Medical Subject Headings::Check Tags::Male KW - Medical Subject Headings::Chemicals and Drugs::Nucleic Acids, Nucleotides, and Nucleosides::Nucleic Acids::RNA::RNA, Messenger KW - Medical Subject Headings::Chemicals and Drugs::Biological Factors::Antigens::Antigens, Surface::Antigens, Differentiation::Antigens, CD::Receptors, Tumor Necrosis Factor, Type II KW - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Carrier Proteins::Adaptor Proteins, Signal Transducing::Smad Proteins::Smad Proteins, Inhibitory::Smad7 Protein KW - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Membrane Proteins::Receptors, Cell Surface::Receptors, Immunologic::Receptors, Pattern Recognition::Toll-Like Receptors KW - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Processes::Gene Expression::Transcription, Genetic::Transcriptome KW - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Prognosis::Treatment Outcome KW - Medical Subject Headings::Chemicals and Drugs::Biological Factors::Intercellular Signaling Peptides and Proteins::Tumor Necrosis Factors::Tumor Necrosis Factor-alpha KW - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Peptides::Antimicrobial Cationic Peptides::Defensins::alpha-Defensins TI - Gene Signatures of Early Response to Anti-TNF Drugs in Pediatric Inflammatory Bowel Disease TY - research article ER -