RT Journal Article
T1 Characterization of COPD Admissions During the First COVID-19 Outbreak.
A1 Cosio, Borja G
A1 Shafiek, Hanaa
A1 Toledo-Pons, Nuria
A1 Iglesias, Amanda
A1 Barcelo, Margalida
A1 Represas-Represas, Cristina
A1 Comeche, Lorena
A1 Catalan, Pablo
A1 Fernandez-Villar, Alberto
A1 Lopez-Campos, Jose Luis
A1 Echave-Sustaeta, Jose
A1 Soler-Cataluna, Juan Jose
K1 COPD exacerbation
K1 hospitalization
K1 inhaled corticosteroids
K1 mortality
AB Exacerbations of COPD (ECOPD) are a frequent cause of hospitalization that seemed to ameliorate during the COVID outbreak. We aimed to evaluate the clinical characteristics of COPD-related hospital admissions and mortality in relation to the presence of COVID-19. We conducted a case-control study of patients admitted in four teaching hospitals throughout Spain between March 15 and April 30, 2020. Hospital admissions of respiratory cause with and without PCR-proven SARS-CoV-2 infection in patients with COPD were evaluated. Baseline and episode-related clinical characteristics were analyzed. Logistic regression analysis was performed to evaluate the risk for mortality. During the study period, 2101 patients were admitted for respiratory worsening, 1200 (57.1%) with COVID-19. A total of 228 (10.8%) were admitted due to COPD worsening, of whom 52 (22.8%) tested positive for COVID-19. COPD patients with COVID-19, when compared to those without COVID-19, were more frequently males with better lung function (FEV1 postbronchodilator 71% vs 46% respectively, p Hospitalizations for ECOPD without COVID-19 were more frequent than COPD with COVID-19 during the first outbreak, but the latter were associated with higher mortality and low eosinophil counts that warrant further analysis.
YR 2021
FD 2021-06-03
LK http://hdl.handle.net/10668/17987
UL http://hdl.handle.net/10668/17987
LA en
DS RISalud
RD Apr 11, 2025