RT Journal Article
T1 Adverse hepatic reactions associated with calcium carbimide and disulfiram therapy: is there still a role for these drugs?
A1 Verge González, Carmen
A1 Lucena González, María Isabel
A1 López-Torres, Enrique
A1 Puche-García, María José
A1 Fraga, Enrique
A1 Romero-Gómez, Manuel
A1 Andrade Bellido, Raúl Jesús
K1 Calcium carbimide
K1 Hepatotoxicity
K1 Disuasivos de Alcohol
K1 Cianamida
K1 Disulfiram
K1 Interacciones de Drogas
K1 Hígado
K1 Enfermedad Hepática Inducida por Drogas
K1 Femenino
K1 Humanos
K1 Masculino
K1 Mediana Edad
K1 Adulto
AB Disulfiram and calcium carbimide are two alcohol deterrants widely used in alcoholism treatment, however, there exist great concerns over their safety. Reports on hepatotoxicity, mainly related to disulfiram therapy, have been published. The hepatotoxic potential of calcium carbimide is less well characterized. Here, we describe four cases of liver damage related to this therapeutic group that were submitted to a Registry of hepatotoxicity and point out the limitations that we face when prescribing these compounds. A reassessment of the role of these compounds in the management of alcohol dependence is clearly needed.
PB Baishideng Publishing Group Co. Limited
SN 1007-9327
YR 2006
FD 2006-08-21
LK http://hdl.handle.net/10668/815
UL http://hdl.handle.net/10668/815
LA en
NO Verge González C, Lucena González MI, López-Torres E, Puche-García MJ, Fraga E, Romero-Gómez M, et al. Adverse hepatic reactions associated with calcium carbimide and disulfiram therapy: is there still a role for these drugs? World J. Gastroenterol.. 2006;12(31):5078-80
NO Case Reports; Journal Article; Research Support, Non-U.S. Gov't;
DS RISalud
RD Apr 18, 2025