TY - JOUR AU - Martín-Guerrero, Sandra M AU - Muñoz-Gámez, José A AU - Carrasco, María-Carmen AU - Salmerón, Javier AU - Martín-Estebané, María AU - Cuadros, Miguel A AU - Navascués, Julio AU - Martín-Oliva, David PY - 2017 DO - 10.1371/journal.pone.0187130 UR - http://hdl.handle.net/10668/11733 T2 - PloS one AB - Poly(ADP-ribose)polymerases (PARPs) are a family of NAD+ consuming enzymes that play a crucial role in many cellular processes, most clearly in maintaining genome integrity. Here, we present an extensive analysis of the alteration of mitochondrial... LA - en KW - Cell Line KW - Hepatocytes KW - Humans KW - Hydrogen Peroxide KW - Mitochondria KW - Poly(ADP-ribose) Polymerase Inhibitors KW - Reactive Oxygen Species TI - Poly(ADP-ribose)polymerases inhibitors prevent early mitochondrial fragmentation and hepatocyte cell death induced by H2O2. TY - research article VL - 12 ER -