RT Journal Article
T1 Rationale for the treatment of Wilms tumour in the UMBRELLA SIOP-RTSG 2016 protocol
A1 van den Heuvel-Eibrink, Marry M.
A1 Hol, Janna A.
A1 Pritchard-Jones, Kathy
A1 van Tinteren, Harm
A1 Furtwangler, Rhoikos
A1 Verschuur, Arnauld C.
A1 Vujanic, Gordan M.
A1 Leuschner, Ivo
A1 Brok, Jesper
A1 Rube, Christian
A1 Smets, Anne M.
A1 Janssens, Geert O.
A1 Godzinski, Jan
A1 Ramirez-Villar, Gema L.
A1 de Camargo, Beatriz
A1 Segers, Heidi
A1 Collini, Paola
A1 Gessler, Manfred
A1 Bergeron, Christophe
A1 Spreafico, Filippo
A1 Graf, Norbert
A1 Int Soc Paediat Oncology Renal Tu, 
K1 Randomized controlled-trial
K1 Preoperative chemotherapy
K1 Stage-ii
K1 International-society
K1 Pulmonary metastases
K1 Favorable histology
K1 Intermediate-risk
K1 Initial treatment
K1 Actinomycin-d
K1 Renal tumors
AB The Renal Tumour Study Group of the International Society of Paediatric Oncology (SIOP-RTSG) has developed a new protocol for the diagnosis and treatment of childhood renal tumours, the UMBRELLA SIOP-RTSG 2016 (the UMBRELLA protocol), to continue international collaboration in the treatment of childhood renal tumours. This protocol will support integrated biomarker and imaging research, focussing on assessing the independent prognostic value of genomic changes within the tumour and the volume of the blastemal component that survives preoperative chemotherapy. Treatment guidelines for Wilms tumours in the UMBRELLA protocol include recommendations for localized, metastatic, and bilateral disease, for all age groups, and for relapsed disease. These recommendations have been established by a multidisciplinary panel of leading experts on renal tumours within the SIOP-RTSG. The UMBRELLA protocol should promote international collaboration and research and serve as the SIOP-RTSG best available treatment standard.
PB Nature publishing group
SN 1759-4812
YR 2017
FD 2017-12-01
LK http://hdl.handle.net/10668/18902
UL http://hdl.handle.net/10668/18902
LA en
DS RISalud
RD Apr 7, 2025