TY - JOUR AU - Metwally, Mayada AU - Bayoumi, Ali AU - Khan, Anis AU - Adams, Leon A AU - Aller, Rocio AU - García-Monzón, Carmelo AU - Arias-Loste, María Teresa AU - Bugianesi, Elisabetta AU - Miele, Luca AU - Anna, Alisi AU - Latchoumanin, Olivier AU - Han, Shuanglin AU - Alenizi, Shafi AU - Sharkawy, Rasha El AU - Elattar, Afaf AU - Gallego-Durán, Rocio AU - Fischer, Janett AU - Berg, Thomas AU - Liddle, Christopher AU - Romero-Gomez, Manuel AU - George, Jacob AU - Eslam, Mohammed PY - 2021 DO - 10.1016/j.ebiom.2021.103521 UR - http://hdl.handle.net/10668/18371 T2 - EBioMedicine AB - Liver fibrosis risk is a heritable trait, the outcome of which is the net deposition of extracellular matrix by hepatic stellate cell-derived myofibroblasts. Whereas nucleotide sequence variations have been extensively studied in liver fibrosis, the... LA - en KW - Fibrosis KW - MAFLD KW - TGFβ KW - XPO4 KW - Adult KW - Animals KW - Cell Line KW - DNA Copy Number Variations KW - Fatty Liver KW - Female KW - Humans KW - Karyopherins KW - Liver Cirrhosis KW - Male KW - Mice KW - Mice, Inbred C57BL KW - Middle Aged KW - Smad3 Protein KW - Smad4 Protein KW - Transforming Growth Factor beta TI - Copy number variation and expression of exportin-4 associates with severity of fibrosis in metabolic associated fatty liver disease. TY - research article VL - 70 ER -