RT Journal Article T1 Association of wrist and ambient temperature with cold-induced brown adipose tissue and skeletal muscle [18F]FDG uptake in young adults. A1 Martinez-Tellez, Borja A1 Xu, Huiwen A1 Sanchez-Delgado, Guillermo A1 Acosta, Francisco M A1 Rensen, Patrick C N A1 Llamas-Elvira, Jose M A1 Ruiz, Jonatan R K1 Temperatus K1 brown fat K1 glucose uptake K1 iButton K1 outdoor temperature K1 seasonal variation AB Brown adipose tissue (BAT) activity is influenced by the outdoor temperature variation. However, people spend most of their time indoors, especially in colder regions and during cold seasons. Therefore, outdoor temperature is probably not an accurate tool to quantify the exposure of the participants before BAT quantification. We studied the association of wrist and personal environmental temperatures with cold-induced BAT and skeletal muscle [18F]fluorodeoxyglucose ([18F]FDG) uptake in adults. A total of 74 participants wore two iButtons during 7 days to measure wrist temperature (WT) and personal level of environmental temperature (Personal-ET). Thereafter, we performed a 2-h personalized cooling protocol before performing an [18F]FDG-PET/CT scan. WT was negatively associated with BAT volume ( R2 = 0.122; P = 0.002) and BAT activity [standardized uptake value (SUV)peak, R2 = 0.083; P = 0.012]. Moreover, Personal-ET was negatively associated with BAT volume ( R2 = 0.164; P PB American Physiological Society SN 0363-6119 YR 2018 FD 2018-10-19 LK http://hdl.handle.net/10668/13135 UL http://hdl.handle.net/10668/13135 LA en NO Martinez-Tellez B, Xu H, Sanchez-Delgado G, Acosta FM, Rensen PCN, et al. Association of wrist and ambient temperature with cold-induced brown adipose tissue and skeletal muscle [18F]FDG uptake in young adults. Am J Physiol Regul Integr Comp Physiol. 2018 Dec 1;315(6):R1281-R1288. DS RISalud RD Apr 7, 2025