%0 Journal Article
%A Martinez-Tellez, Borja
%A Xu, Huiwen
%A Sanchez-Delgado, Guillermo
%A Acosta, Francisco M
%A Rensen, Patrick C N
%A Llamas-Elvira, Jose M
%A Ruiz, Jonatan R
%T Association of wrist and ambient temperature with cold-induced brown adipose tissue and skeletal muscle [18F]FDG uptake in young adults.
%D 2018
%@ 0363-6119
%U http://hdl.handle.net/10668/13135
%X Brown adipose tissue (BAT) activity is influenced by the outdoor temperature variation. However, people spend most of their time indoors, especially in colder regions and during cold seasons. Therefore, outdoor temperature is probably not an accurate tool to quantify the exposure of the participants before BAT quantification. We studied the association of wrist and personal environmental temperatures with cold-induced BAT and skeletal muscle [18F]fluorodeoxyglucose ([18F]FDG) uptake in adults. A total of 74 participants wore two iButtons during 7 days to measure wrist temperature (WT) and personal level of environmental temperature (Personal-ET). Thereafter, we performed a 2-h personalized cooling protocol before performing an [18F]FDG-PET/CT scan. WT was negatively associated with BAT volume ( R2 = 0.122; P = 0.002) and BAT activity [standardized uptake value (SUV)peak, R2 = 0.083; P = 0.012]. Moreover, Personal-ET was negatively associated with BAT volume ( R2 = 0.164; P
%K Temperatus
%K brown fat
%K glucose uptake
%K iButton
%K outdoor temperature
%K seasonal variation
%~