TY  - JOUR
AU  - San José-Enériz, Edurne
AU  - Román-Gómez, José
AU  - Jiménez-Velasco, Antonio
AU  - Garate, Leire
AU  - Martin, Vanesa
AU  - Cordeu, Lucia
AU  - Vilas-Zornoza, Amaia
AU  - Rodríguez-Otero, Paula
AU  - Calasanz, María José
AU  - Prósper, Felipe
AU  - Agirre, Xabier
PY  - 2009
DO  - 10.1186/1476-4598-8-69
UR  - http://hdl.handle.net/10668/1209
T2  - Molecular cancer
AB  - The development of Imatinib Mesylate (IM), the first specific inhibitor of BCR-ABL1, has had a major impact in patients with Chronic Myeloid Leukemia (CML), establishing IM as the standard therapy for CML. Despite the clinical success obtained with...
LA  - en
PB  - BioMed Central
KW  - Antineoplásicos
KW  - Análisis de cluster
KW  - Resistencia a antineoplásicos
KW  - Leucemia mielogenosa crónica BCR-ABL positiva
KW  - MicroARN
KW  - Pirimidinas
KW  - Reacción en cadena de la polimerasa de transcriptasa inversa
KW  - Perfiles de expresión génica
KW  - Medical Subject Headings::Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Therapeutic Uses::Antineoplastic Agents
KW  - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Statistics as Topic::Cluster Analysis
KW  - Medical Subject Headings::Phenomena and Processes::Physiological Phenomena::Pharmacological Phenomena::Drug Resistance::Drug Resistance, Neoplasm
KW  - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Genetic Techniques::Gene Expression Profiling
KW  - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans
KW  - Medical Subject Headings::Diseases::Hemic and Lymphatic Diseases::Hematologic Diseases::Bone Marrow Diseases::Myeloproliferative Disorders::Leukemia, Myelogenous, Chronic, BCR-ABL Positive
KW  - Medical Subject Headings::Chemicals and Drugs::Nucleic Acids, Nucleotides, and Nucleosides::Nucleic Acids::RNA::RNA, Antisense::MicroRNAs
KW  - Medical Subject Headings::Chemicals and Drugs::Heterocyclic Compounds::Heterocyclic Compounds, 1-Ring::Piperazines
KW  - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Genetic Techniques::Nucleic Acid Amplification Techniques::Polymerase Chain Reaction::Reverse Transcriptase Polymerase Chain Reaction
TI  - MicroRNA expression profiling in Imatinib-resistant Chronic Myeloid Leukemia patients without clinically significant ABL1-mutations.
TY  - research article
ER  -