TY  - JOUR
AU  - Bleriot, Ines
AU  - Blasco, Lucia
AU  - Delgado-Valverde, Mercedes
AU  - Gual-de-Torella, Ana
AU  - Ambroa, Anton
AU  - Fernandez-Garcia, Laura
AU  - Lopez, Maria
AU  - Oteo-Iglesias, Jesus
AU  - Wood, Thomas K.
AU  - Pascual, Alvaro
AU  - Bou, German
AU  - Fernandez-Cuenca, Felipe
AU  - Tomas, Maria
PY  - 2020
DO  - 10.3390/toxins12090566
UR  - http://hdl.handle.net/10668/3709
T2  - Toxins
AB  - Although the failure of antibiotic treatment is normally attributed to resistance, tolerance and persistence display a significant role in the lack of response to antibiotics. Due to the fact that several nosocomial pathogens show a high level of...
LA  - en
PB  - MDPI
KW  - Tolerance
KW  - Persistence
KW  - Cross-resistance
KW  - Toxin-antitoxin system
KW  - PemI/PemK
KW  - Klebsiella pneumoniae
KW  - Combinación de medicamentos
KW  - Farmacorresistencia bacteriana
KW  - Sistemas toxina-antitoxina
KW  - Transcriptoma
KW  - Medical Subject Headings::Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Therapeutic Uses::Anti-Infective Agents::Anti-Bacterial Agents
KW  - Medical Subject Headings::Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Therapeutic Uses::Anti-Infective Agents::Anti-Infective Agents, Local
KW  - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Bacterial Proteins
KW  - Medical Subject Headings::Chemicals and Drugs::Organic Chemicals::Amidines::Guanidines::Biguanides::Chlorhexidine
KW  - Medical Subject Headings::Chemicals and Drugs::Pharmaceutical Preparations::Drug Combinations
KW  - Medical Subject Headings::Phenomena and Processes::Physiological Phenomena::Pharmacological Phenomena::Pharmacological Processes::Drug Tolerance
KW  - Medical Subject Headings::Chemicals and Drugs::Organic Chemicals::Amides::Lactams::beta-Lactams::Carbapenems::Thienamycins::Imipenem
KW  - Medical Subject Headings::Organisms::Bacteria::Gram-Negative Bacteria::Gram-Negative Facultatively Anaerobic Rods::Enterobacteriaceae::Klebsiella::Klebsiella pneumoniae
KW  - Medical Subject Headings::Phenomena and Processes::Physical Phenomena::Time::Time Factors
KW  - Medical Subject Headings::Chemicals and Drugs::Enzymes and Coenzymes::Enzymes::Hydrolases::Amidohydrolases::beta-Lactamases
KW  - Medical Subject Headings::Phenomena and Processes::Microbiological Phenomena::Bacterial Physiological Phenomena::Drug Resistance, Bacterial
KW  - Toxin-Antitoxin Systems
TI  - Mechanisms of Tolerance and Resistance to Chlorhexidine in Clinical Strains of Klebsiella pneumoniae Producers of Carbapenemase: Role of New Type II Toxin-Antitoxin System, PemIK
TY  - research article
ER  -