RT Journal Article T1 International Variability in Gastrointestinal Decontamination With Acute Poisonings. A1 Mintegi, Santiago A1 Dalziel, Stuart R A1 Azkunaga, Beatriz A1 Prego, Javier A1 Arana-Arri, Eunate A1 Acedo, Yordana A1 Martinez-Indart, Lorea A1 Benito, Javier A1 Kuppermann, Nathan A1 Pediatric Emergency Research Networks (PERN) Poisoning Working Group, AB Identifying international differences in the management of acute pediatric poisonings may help improve the quality of care. The objective of this study was to assess the international variation and appropriateness of gastrointestinal decontamination (GID) procedures performed in children and adolescents who present with acute poisonings to emergency departments. This was an international, multicenter, cross-sectional prospective study including children We included 1688 patients, 338 of whom (20.0%, 95% confidence interval 18.1%-22.0%) underwent the following GID procedures: activated charcoal (166, 49.1%), activated charcoal and gastric lavage (122, 36.1%), gastric lavage (47, 13.9%), and ipecac (3, 0.9%). In 155 (45.8%, 40.5%-51.2%), the GID procedure was considered appropriate, with significant differences between regions. Independent risk factors for GID procedures included age, toxin category, mechanism of poisoning, absence of symptoms, and the region where the intoxication occurred (P Globally, there are substantial differences in the use and appropriateness of GID procedures in the management of pediatric poisonings. International best practices need to be better implemented. YR 2017 FD 2017 LK https://hdl.handle.net/10668/26616 UL https://hdl.handle.net/10668/26616 LA en DS RISalud RD Apr 8, 2025