TY - JOUR AU - Mayor-Olea, Alvaro AU - Callejón, Gonzalo AU - Palomares, Arturo R AU - Jiménez, Ana J AU - Gaitán, María Jesús AU - Rodríguez, Alfonso AU - Ruiz, Maximiliano AU - Reyes-Engel, Armando PY - 2008 DO - 10.1186/1471-2350-9-104 UR - http://hdl.handle.net/10668/1309 T2 - BMC medical genetics AB - BACKGROUNDThe prevalence of genotypes of the 677C>T polymorphism for the MTHFR gene varies among humans. In previous studies, we found changes in the genotypic frequencies of this polymorphism in populations of different ages, suggesting that this... LA - en PB - BioMed Central KW - Feto abortado KW - Frecuencia de los Genes KW - Genotipo KW - Metilenotetrahidrofolato reductasa (NADPH2) KW - Reacción en cadena de la polimerasa KW - Polimorfismo genético KW - Selección genética KW - España KW - Medical Subject Headings::Named Groups::Persons::Age Groups::Adult KW - Medical Subject Headings::Health Care::Health Care Quality, Access, and Evaluation::Quality of Health Care::Epidemiologic Factors::Age Factors KW - Medical Subject Headings::Check Tags::Female KW - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Gene Frequency KW - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genotype KW - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans KW - Medical Subject Headings::Check Tags::Male KW - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Flavoproteins::Methylenetetrahydrofolate Reductase (NADPH2) KW - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Genetic Techniques::Nucleic Acid Amplification Techniques::Polymerase Chain Reaction KW - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Variation::Polymorphism, Genetic KW - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Processes::Selection, Genetic KW - Medical Subject Headings::Geographicals::Geographic Locations::Europe::Spain KW - Medical Subject Headings::Named Groups::Persons::Age Groups::Adult::Young Adult KW - Medical Subject Headings::Anatomy::Embryonic Structures::Fetus::Aborted Fetus TI - Human genetic selection on the MTHFR 677C>T polymorphism. TY - research article ER -