%0 Journal Article
%A Uribarri, Aitor
%A Núñez-Gil, Iván J
%A Aparisi, Alvaro
%A Becerra-Muñoz, Victor M
%A Feltes, Gisela
%A Trabattoni, Daniela
%A Fernández-Rozas, Inmaculada
%A Viana-Llamas, María C
%A Pepe, Martino
%A Cerrato, Enrico
%A Capel-Astrua, Thamar
%A Romero, Rodolfo
%A Castro-Mejía, Alex F
%A El-Battrawy, Ibrahim
%A López-País, Javier
%A D'Ascenzo, Fabrizio
%A Fabregat-Andres, Oscar
%A Bardají, Alfredo
%A Raposeiras-Roubin, Sergio
%A Marín, Francisco
%A Fernández-Ortiz, Antonio
%A Macaya, Carlos
%A Estrada, Vicente
%A HOPE COVID-19 Investigators
%T Impact of renal function on admission in COVID-19 patients: an analysis of the international HOPE COVID-19 (Health Outcome Predictive Evaluation for COVID 19) Registry.
%D 2020
%U http://hdl.handle.net/10668/15851
%X Coronavirus disease 2019 (COVID-19) is a disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Despite its international aggressive extension, with a significant morbidity and mortality, the impact of renal function on its prognosis is uncertain. Analysis from the international HOPE-Registry (NCT04334291). The objective was to evaluate the association between kidney failure severity on admission with the mortality of patients with SARS-CoV-2 infection. Patients were categorized in 3 groups according to the estimated glomerular filtration rate on admission (eGFR > 60 mL/min/1.73 m2, eGFR 30-60 mL/min/1.73 m2 and eGFR  60 mL/min/1.73 m2, eGFR 30-60 mL/min/1.73 m2 and eGFR  758 patients were included: mean age was 66 ± 18 years, and 58.6% of patient were male. Only 8.5% of patients had a history of chronic kidney disease (CKD); however, 30% of patients had kidney dysfunction upon admission (eGFR  60 vs eGFR 30-60 vs and eGFR  Renal failure on admission in patients with SARS-CoV-2 infection is frequent and is associated with a greater number of complications and in-hospital mortality. Our data comes from a multicenter registry and therefore does not allow to have a precise mortality risk assessment. More studies are needed to confirm these findings.
%K Acute kidney injury
%K COVID-19
%K Chronic kidney failure
%K Mortality
%K Prognosis
%K Registry
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