RT Journal Article T1 'Physio-EndEA' Study: A Randomized, Parallel-Group Controlled Trial to Evaluate the Effect of a Supervised and Adapted Therapeutic Exercise Program to Improve Quality of Life in Symptomatic Women Diagnosed with Endometriosis. A1 Salinas-Asensio, Maria Del Mar A1 Ocon-Hernandez, Olga A1 Mundo-Lopez, Antonio A1 Fernandez-Lao, Carolina A1 Peinado, Francisco M A1 Padilla-Vinuesa, Carmen A1 Alvarez-Salvago, Francisco A1 Postigo-Martin, Paula A1 Lozano-Lozano, Mario A1 Lara-Ramos, Ana A1 Arroyo-Morales, Manuel A1 Cantarero-Villanueva, Irene A1 Artacho-Cordon, Francisco K1 endometriosis K1 motor control K1 pain K1 physiotherapy K1 quality of life K1 therapeutic exercise AB The 'Physio-EndEA' study aims to explore the potential benefits of a therapeutic exercise program (focused on lumbopelvic stabilization and tolerance to exertion) on the health-related quality of life (HRQoL) of symptomatic endometriosis women. The present study will use a parallel-group randomized controlled trial design. A total of 22 symptomatic endometriosis women will be randomized 1:1 to the Physio-EndEA or usual care groups. The 'Physio-EndEA' program will consist of a one-week lumbopelvic stabilization learning phase followed by an eight-week phase of stretching, aerobic and resistance exercises focused on the lumbopelvic area that will be sequentially instructed and supervised by a trained physiotherapist (with volume and intensity progression) and adapted daily to the potential of each participant. The primary outcome measure is HRQoL. The secondary outcome measures included clinician-reported outcomes (pressure pain thresholds, muscle thickness and strength, flexibility, body balance and cardiorespiratory fitness) and patient-reported outcomes (pain intensity, physical fitness, chronic fatigue, sexual function, gastrointestinal function and sleep quality). Findings of this study will help to identify cost-effective non-pharmacological options (such as this exercise-based intervention) that may contribute to the improvement of HRQoL in symptomatic endometriosis women. PB MDPI AG YR 2022 FD 2022-01-30 LK http://hdl.handle.net/10668/21025 UL http://hdl.handle.net/10668/21025 LA en NO Salinas-Asensio MDM, Ocón-Hernández O, Mundo-López A, Fernández-Lao C, Peinado FM, Padilla-Vinuesa C, et al. 'Physio-EndEA' Study: A Randomized, Parallel-Group Controlled Trial to Evaluate the Effect of a Supervised and Adapted Therapeutic Exercise Program to Improve Quality of Life in Symptomatic Women Diagnosed with Endometriosis. Int J Environ Res Public Health. 2022 Feb 2;19(3):1738. DS RISalud RD Apr 8, 2025