%0 Journal Article
%A Soriano-Maldonado, Alberto
%A Díez-Fernández, David M
%A Esteban-Simón, Alba
%A Rodríguez-Pérez, Manuel A
%A Artés-Rodríguez, Eva
%A Casimiro-Artés, Miguel A
%A Moreno-Martos, Herminia
%A Toro-de-Federico, Antonio
%A Hachem-Salas, Nur
%A Bartholdy, Cecilie
%A Henriksen, Marius
%A Casimiro-Andújar, Antonio J
%T Effects of a 12-week supervised resistance training program, combined with home-based physical activity, on physical fitness and quality of life in female breast cancer survivors: the EFICAN randomized controlled trial.
%D 2022
%U http://hdl.handle.net/10668/20919
%X This study assessed the effects of 12-week supervised resistance training combined with home-based physical activity on physical fitness, cancer-related fatigue, depressive symptoms, health-related quality of life (HRQoL), and life satisfaction in female breast cancer survivors. A parallel-group, outcome assessor-blinded, randomized controlled trial included 60 female breast cancer survivors who had completed their core treatments within the previous 10 years. Through computer-generated simple randomization, participants were assigned to resistance training (RTG; two sessions/week for 12 weeks plus instructions to undertake ≥ 10,000 steps/d) or control (CG; ≥ 10,000 steps/d only). Outcomes were evaluated at baseline and week 12. Muscular strength was assessed with electromechanical dynamometry. A standardized full-body muscular strength score was the primary outcome. Secondary outcomes included cardiorespiratory fitness, shoulder mobility, cancer-related fatigue, depressive symptoms, HRQoL, and life satisfaction. Thirty-two participants were assigned to RTG (29 achieved ≥ 75% attendance) and 28 to CG (all completed the trial). Intention-to-treat analyses revealed that the standardized full-body muscular strength score increased significantly in the RTG compared to the CG (0.718; 95% CI 0.361-1.074, P  and implication for cancer survivors. In female breast cancer survivors who had completed their core treatments within the past 10 years, adding two weekly sessions of supervised resistance training to a prescription of home-based physical activity for 12 weeks produced a large increase in upper-, lower-, and full-body muscular strength, while other fitness components and patient-reported outcomes did not improve. ISRCTN14601208.
%K Breast cancer
%K Cancer-related fatigue
%K Health-related quality of life
%K Muscular strength
%K Resistance training
%~