RT Journal Article
T1 Keratotic Nodule on The Heel: A Quiz.
A1 Nogueras-Morillas, Paloma
A1 Blasco-Morente, Gonzalo
A1 Espadafor-López, Beatriz
A1 Aneiros-Fernández, José
A1 Tercedor-Sánchez, Jesús
K1 Talón
K1 Inhibinas
K1 Neoplasias
K1 Proteínas de transporte de noradrenalina a través de la membrana plasmática
K1 Trasplante de piel
K1 Tejido subcutáneo
K1 Tiroxina
K1 Tumor de células granulares
AB A 51-year-old man, with a medical history of medullary thyroid carcinoma excised under thyroxine treatment presented with a painful enlarging lesion on his right heel since one year. A 3-cm diameter, greyish, infiltrated nodule with spicules was seen on physical examination (Fig. 1a). A 5-mm surgical excision was made and a total skin graft was used for reconstruction. Histopathology of the total resected tumour revealed pseudoepitheliomatous hyperplasic epidermis and a proliferation located between rete ridges, dermis and superficial hypodermis (Fig. 1b). The proliferation was composed of nets and cordons of cells with granular and abundant PAS-positive cytoplasm. Immunostains showed cytoplasmic positivity for s100 and inhibin (Fig. 1c). Three years later the patient is asymptomatic.
PB Society for Publication of Acta Dermato-Venereologica
SN 0001-5555
YR 2016
FD 2016-03-01
LK http://hdl.handle.net/10668/2193
UL http://hdl.handle.net/10668/2193
LA spa
NO Nogueras-Morillas P, Blasco-Morente G, Espadafor-López B, Aneiros-Fernández J, Tercedor-Sánchez J. Keratotic Nodule on The Heel: A Quiz. Acta Derm. Venereol. 2016; 96(3):427-431
NO JOURNAL ARTICLE;
DS RISalud
RD Apr 11, 2025