RT Journal Article
T1 Effect of Supervised Resistance Training on Arm Volume, Quality of Life and Physical Perfomance Among Women at High Risk for Breast Cancer-Related Lymphedema: A Study Protocol for a Randomized Controlled Trial (STRONG-B).
A1 Ramirez-Parada, Karol
A1 Lopez-Garzon, Maria
A1 Sanchez-Rojel, Cesar
A1 Petric-Guajardo, Militza
A1 Alfaro-Barra, Margarita
A1 Fernandez-Verdejo, Rodrigo
A1 Reyes-Ponce, Alvaro
A1 Merino-Pereira, Gina
A1 Cantarero-Villanueva, Irene
K1 breast cancer lymphedema
K1 breast neoplasms
K1 physical therapy specialty
K1 quality of life
K1 resistance training
AB To determine the preventive effects of supervised resistance training on arms volume, quality of life, physical performance, and handgrip strength in Chilean women at high risk for breast cancer-related lymphedema (BCRL) undergoing chemotherapy. Randomized control trial. One hundred and six women at high risk for breast cancer-related lymphedema aged 18 to 70 years. Participants will be randomized into two groups: [a] intervention, who will receive 12 weeks of supervised resistance training (STRONG-B) during adjuvant chemotherapy; and [b] control, who will receive education to promote lymphatic and venous return, maintain range of motion, and promote physical activity. The primary outcome will be arms volume measured with an optoelectric device (perometer NT1000). Secondary outcomes will be quality of life, handgrip strength, and physical performance. Primary and secondary outcomes will be measured at baseline, just after the intervention, and 3 and 6 months after. Statistical analysis will be performed following intention-to-treat and per-protocol approaches. The treatment effect will be calculated using linear mixed models. The STRONG-B will be a tailored supervised resistance training that attempts to prevent or mitigate BCRL in a population that, due to both intrinsic and extrinsic factors, will commonly suffer from BCRL. [https://clinicaltrials.gov/ct2/show/NCT04821609], identifier NCT04821609.
PB Frontiers Research Foundation
SN 2234-943X
YR 2022
FD 2022-02-01
LK http://hdl.handle.net/10668/20681
UL http://hdl.handle.net/10668/20681
LA en
NO Ramírez-Parada K, Lopez-Garzon M, Sanchez-Rojel C, Petric-Guajardo M, Alfaro-Barra M, Fernández-Verdejo R, et al. Effect of Supervised Resistance Training on Arm Volume, Quality of Life and Physical Perfomance Among Women at High Risk for Breast Cancer-Related Lymphedema: A Study Protocol for a Randomized Controlled Trial (STRONG-B). Front Oncol. 2022 Mar 1;12:850564.
DS RISalud
RD Jul 29, 2025