RT Journal Article
T1 Prevalence and distribution of peripheral musculoskeletal manifestations in spondyloarthritis including psoriatic arthritis: results of the worldwide, cross-sectional ASAS-PerSpA study.
A1 Lopez-Medina, Clementina
A1 Molto, Anna
A1 Sieper, Joachim
A1 Duruöz, Tuncay
A1 Kiltz, Uta
A1 Elzorkany, Bassel
A1 Hajjaj-Hassouni, Najia
A1 Burgos-Vargas, Ruben
A1 Maldonado-Cocco, Jose
A1 Ziade, Nelly
A1 Gavali, Meghna
A1 Navarro-Compan, Victoria
A1 Luo, Shue-Fen
A1 Monti, Sara
A1 Tae-Jong, Kim
A1 Kishimoto, Mitsumasa
A1 Pimentel-Santos, F M
A1 Gu, Jieruo
A1 Schiotis, Ruxandra
A1 van Gaalen, Floris A
A1 Geher, Pal
A1 Magrey, Marina
A1 Ibañez Vodnizza, Sebastian E
A1 Bautista-Molano, Wilson
A1 Maksymowych, Walter
A1 Machado, Pedro M
A1 Landewe, Robert
A1 van der Heijde, Desiree
A1 Dougados, Maxime
K1 Ankylosing
K1 Arthritis
K1 Juvenile
K1 Psoriatic
K1 Spondylitis
AB To characterise peripheral musculoskeletal involvement in patients with spondyloarthritis (SpA) including psoriatic arthritis (PsA), across the world. Cross-sectional study with 24 participating countries. Patients with a diagnosis of axial SpA (axSpA), peripheral SpA (pSpA) or PsA according to their rheumatologist were included. The investigators were asked which diagnosis out of a list of six (axSpA, PsA, pSpA, inflammatory bowel disease-associated SpA, reactive arthritis or juvenile SpA (Juv-SpA)) fitted the patient best. Peripheral manifestations (ie, peripheral joint disease, enthesitis, dactylitis and root joint disease), their localisation and treatments were evaluated. A total of 4465 patients were included (61% men, mean age 44.5 years) from four geographic areas: Latin America (n=538), Europe plus North America (n=1677), Asia (n=975) and the Middle East plus North Africa (n=1275). Of those, 78% had ever suffered from at least one peripheral musculoskeletal manifestation; 57% had peripheral joint disease, 44% had enthesitis and 15% had dactylitis. Latin American had far more often peripheral joint disease (80%) than patients from other areas. Patients with PsA had predominantly upper limb and small joint involvement (52%).Hip and shoulder involvement was found in 34% of patients. The prevalence of enthesitis ranged between 41% in patients with axSpA and 65% in patients with Juv-SpA. Dactylitis was most frequent among patients with PsA (37%). These results suggest that all peripheral features can be found in all subtypes of SpA, and that differences are quantitative rather than qualitative. In a high proportion of patients, axial and peripheral manifestations coincided. These findings reconfirm SpA clinical subtypes are descendants of the same underlying disease, called SpA.
PB BMJ Group
YR 2020
FD 2020-12-12
LK http://hdl.handle.net/10668/16989
UL http://hdl.handle.net/10668/16989
LA en
NO López-Medina C, Molto A, Sieper J, Duruöz T, Kiltz U, Elzorkany B, et al.  Prevalence and distribution of peripheral musculoskeletal manifestations in spondyloarthritis including psoriatic arthritis: results of the worldwide, cross-sectional ASAS-PerSpA study. RMD Open. 2021 Jan;7(1):e001450
DS RISalud
RD Apr 7, 2025