%0 Journal Article
%A Lopez-Medina, Clementina
%A Molto, Anna
%A Sieper, Joachim
%A Duruöz, Tuncay
%A Kiltz, Uta
%A Elzorkany, Bassel
%A Hajjaj-Hassouni, Najia
%A Burgos-Vargas, Ruben
%A Maldonado-Cocco, Jose
%A Ziade, Nelly
%A Gavali, Meghna
%A Navarro-Compan, Victoria
%A Luo, Shue-Fen
%A Monti, Sara
%A Tae-Jong, Kim
%A Kishimoto, Mitsumasa
%A Pimentel-Santos, F M
%A Gu, Jieruo
%A Schiotis, Ruxandra
%A van Gaalen, Floris A
%A Geher, Pal
%A Magrey, Marina
%A Ibañez Vodnizza, Sebastian E
%A Bautista-Molano, Wilson
%A Maksymowych, Walter
%A Machado, Pedro M
%A Landewe, Robert
%A van der Heijde, Desiree
%A Dougados, Maxime
%T Prevalence and distribution of peripheral musculoskeletal manifestations in spondyloarthritis including psoriatic arthritis: results of the worldwide, cross-sectional ASAS-PerSpA study.
%D 2020
%U http://hdl.handle.net/10668/16989
%X To characterise peripheral musculoskeletal involvement in patients with spondyloarthritis (SpA) including psoriatic arthritis (PsA), across the world. Cross-sectional study with 24 participating countries. Patients with a diagnosis of axial SpA (axSpA), peripheral SpA (pSpA) or PsA according to their rheumatologist were included. The investigators were asked which diagnosis out of a list of six (axSpA, PsA, pSpA, inflammatory bowel disease-associated SpA, reactive arthritis or juvenile SpA (Juv-SpA)) fitted the patient best. Peripheral manifestations (ie, peripheral joint disease, enthesitis, dactylitis and root joint disease), their localisation and treatments were evaluated. A total of 4465 patients were included (61% men, mean age 44.5 years) from four geographic areas: Latin America (n=538), Europe plus North America (n=1677), Asia (n=975) and the Middle East plus North Africa (n=1275). Of those, 78% had ever suffered from at least one peripheral musculoskeletal manifestation; 57% had peripheral joint disease, 44% had enthesitis and 15% had dactylitis. Latin American had far more often peripheral joint disease (80%) than patients from other areas. Patients with PsA had predominantly upper limb and small joint involvement (52%).Hip and shoulder involvement was found in 34% of patients. The prevalence of enthesitis ranged between 41% in patients with axSpA and 65% in patients with Juv-SpA. Dactylitis was most frequent among patients with PsA (37%). These results suggest that all peripheral features can be found in all subtypes of SpA, and that differences are quantitative rather than qualitative. In a high proportion of patients, axial and peripheral manifestations coincided. These findings reconfirm SpA clinical subtypes are descendants of the same underlying disease, called SpA.
%K Ankylosing
%K Arthritis
%K Juvenile
%K Psoriatic
%K Spondylitis
%~