%0 Journal Article
%A Pendón-Ruiz de Mier, María Victoria
%A Vergara, Noemí
%A Rodelo-Haad, Cristian
%A López-Zamorano, María Dolores
%A Membrives-González, Cristina
%A López-Baltanás, Rodrigo
%A Muñoz-Castañeda, Juan Rafael
%A Caravaca, Francisco
%A Martín-Malo, Alejandro
%A Felsenfeld, Arnold J.
%A De la Torre, Eugenio J.
%A Soriano, Sagrario
%A Santamaría, Rafael
%A Rodríguez, Mariano
%T Assessment of Inorganic Phosphate Intake by the Measurement of the Phosphate/Urea Nitrogen Ratio in Urine
%D 2021
%U http://hdl.handle.net/10668/4014
%X In chronic kidney disease (CKD) patients, it would be desirable to reduce the intake of inorganic phosphate (P) rather than limit the intake of P contained in proteins. Urinary excretion of P should reflect intestinal absorption of P(inorganic plus protein-derived). The aim of the present study is to determine whether the ratio of urinary P to urinary urea nitrogen (P/UUN ratio) helps identify patients with a high intake of inorganic P.A cross-sectional study was performed in 71 patients affected by metabolic syndrome with CKD (stages 2-3) with normal serum P concentration. A 3-day dietary survey was performed to estimate the average daily amount and the source of P ingested. The daily intake ofPwas1086.5 ± 361.3mg/day; 64% contained in animal proteins, 22% in vegetable proteins, and 14% as inorganic P. The total amount of P ingested did not correlate with daily phosphaturia, but it did correlate with the P/UUN ratio (p < 0.018). Patients with the highest tertile of the P/UUN ratio >71.1 mg/g presented more abundant inorganic P intake (p < 0.038).The P/UUN ratio is suggested to be a marker of inorganic P intake. This finding might be useful in clinical practices to identify the source of dietary P and to make personalized dietary recommendations directed to reduce inorganic P intake.
%K Phosphaturia
%K Phosphate intake
%K FGF23
%K PTH
%K CKD
%K Hipofosfatemia familiar
%K Factor de crecimiento fibroblástico 23
%K Hormona paratiroidea
%K Insuficiencia renal crónica
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