%0 Journal Article
%A Andamoyo-Castañeda, Alberto 
%A Godoy-Diaz, Daniel Jesus
%A Ayala-Blanca, Maria 
%T B-cell chronic lymphocytic leukemia with bilateral ear involvement.
%D 2022
%U http://hdl.handle.net/10668/21798
%X A 66-year-old woman presented with multiple, painless, plum-colored nodules in both ears for the past year, associated with partial destruction of the auricular cartilage [Figures 1a and b]. The histopathologic examination revealed a monomorphic lymphocyte infiltrate that expressed CD5, CD20, CD23, CD43 and was negative for CD3, CD10, cyclin D1, Bcl2, and Bcl6. The findings were compatible with B-cell chronic lymphocytic leukemia (CLL-B). The myelogram done showed a lymphocyte clone with a similar immunohistochemical profile. Pan-body CT-scan and blood tests were normal. This patient responded well to local radiation therapy (total dose of 16 Gy) with resolution of the nodules.
%K Lymphocytes
%K Radiotherapy
%K Hematologic Tests
%K Ear Cartilage
%K Prunus domestica
%~