RT Journal Article T1 Meat consumption and mortality - results from the European Prospective Investigation into Cancer and Nutrition. A1 Rohrmann, Sabine A1 Overvad, Kim A1 Bueno-de-Mesquita, H Bas A1 Jakobsen, Marianne U A1 Egeberg, Rikke A1 Tjønneland, Anne A1 Nailler, Laura A1 Boutron-Ruault, Marie-Christine A1 Clavel-Chapelon, Françoise A1 Krogh, Vittorio A1 Palli, Domenico A1 Panico, Salvatore A1 Tumino, Rosario A1 Ricceri, Fulvio A1 Bergmann, Manuela M A1 Boeing, Heiner A1 Li, Kuanrong A1 Kaaks, Rudolf A1 Khaw, Kay-Tee A1 Wareham, Nicholas J A1 Crowe, Francesca L A1 Key, Timothy J A1 Naska, Androniki A1 Trichopoulou, Antonia A1 Trichopoulos, Dimitirios A1 Leenders, Max A1 Peeters, Petra H M A1 Engeset, Dagrun A1 Parr, Christine L A1 Skeie, Guri A1 Jakszyn, Paula A1 Sanchez-Perez, Maria-Jose A1 Huerta, José M A1 Redondo, M Luisa A1 Barricarte, Aurelio A1 Amiano, Pilar A1 Drake, Isabel A1 Sonestedt, Emily A1 Hallmans, Göran A1 Johansson, Ingegerd A1 Fedirko, Veronika A1 Romieux, Isabelle A1 Ferrari, Pietro A1 Norat, Teresa A1 Vergnaud, Anne C A1 Riboli, Elio A1 Linseisen, Jakob K1 Mortality K1 Cohort K1 Europe K1 cardiovascular K1 cancer K1 Diet K1 Meat K1 Enfermedades cardiovasculares K1 Estudios de cohortes K1 Neoplasias AB BACKGROUNDRecently, some US cohorts have shown a moderate association between red and processed meat consumption and mortality supporting the results of previous studies among vegetarians. The aim of this study was to examine the association of red meat, processed meat, and poultry consumption with the risk of early death in the European Prospective Investigation into Cancer and Nutrition (EPIC).METHODSIncluded in the analysis were 448,568 men and women without prevalent cancer, stroke, or myocardial infarction, and with complete information on diet, smoking, physical activity and body mass index, who were between 35 and 69 years old at baseline. Cox proportional hazards regression was used to examine the association of meat consumption with all-cause and cause-specific mortality.RESULTSAs of June 2009, 26,344 deaths were observed. After multivariate adjustment, a high consumption of red meat was related to higher all-cause mortality (hazard ratio (HR) = 1.14, 95% confidence interval (CI) 1.01 to 1.28, 160+ versus 10 to 19.9 g/day), and the association was stronger for processed meat (HR = 1.44, 95% CI 1.24 to 1.66, 160+ versus 10 to 19.9 g/day). After correction for measurement error, higher all-cause mortality remained significant only for processed meat (HR = 1.18, 95% CI 1.11 to 1.25, per 50 g/d). We estimated that 3.3% (95% CI 1.5% to 5.0%) of deaths could be prevented if all participants had a processed meat consumption of less than 20 g/day. Significant associations with processed meat intake were observed for cardiovascular diseases, cancer, and 'other causes of death'. The consumption of poultry was not related to all-cause mortality.CONCLUSIONSThe results of our analysis support a moderate positive association between processed meat consumption and mortality, in particular due to cardiovascular diseases, but also to cancer. PB BioMed Central SN 1741-7015 YR 2013 FD 2013-03-07 LK http://hdl.handle.net/10668/1282 UL http://hdl.handle.net/10668/1282 LA en NO Rohrmann S, Overvad K, Bueno-de-Mesquita HB, Jakobsen MU, Egeberg R, Tjønneland A, et al. Meat consumption and mortality--results from the European Prospective Investigation into Cancer and Nutrition. BMC Med. 2013; 11:63 NO Journal Article; Research Support, Non-U.S. Gov't; DS RISalud RD Apr 8, 2025