TY - JOUR AU - Forero-Castro, Maribel AU - Robledo, Cristina AU - Benito, Rocío AU - Bodega-Mayor, Irene AU - Rapado, Inmaculada AU - Hernández-Sánchez, María AU - Abáigar, María AU - Maria Hernández-Sánchez, Jesús AU - Quijada-Álamo, Miguel AU - María Sánchez-Pina, José AU - Sala-Valdés, Mónica AU - Araujo-Silva, Fernanda AU - Kohlmann, Alexander AU - Luis Fuster, José AU - Arefi, Maryam AU - de Las Heras, Natalia AU - Riesco, Susana AU - Rodríguez, Juan N AU - Hermosín, Lourdes AU - Ribera, Jordi AU - Camos Guijosa, Mireia AU - Ramírez, Manuel AU - de Heredia Rubio, Cristina Díaz AU - Barragán, Eva AU - Martínez, Joaquín AU - Ribera, José M AU - Fernández-Ruiz, Elena AU - Hernández-Rivas, Jesús-María PY - 2017 DO - 10.1038/bjc.2017.152 UR - http://hdl.handle.net/10668/11250 T2 - British journal of cancer AB - In B-cell precursor acute lymphoblastic leukaemia (B-ALL), the identification of additional genetic alterations associated with poor prognosis is still of importance. We determined the frequency and prognostic impact of somatic mutations in children... LA - en KW - Adolescent KW - Adult KW - Aged KW - Aged, 80 and over KW - B-Lymphocytes KW - Biomarkers, Tumor KW - Child KW - Child, Preschool KW - Disease-Free Survival KW - Female KW - Gene Expression Regulation, Neoplastic KW - High-Throughput Nucleotide Sequencing KW - Humans KW - Infant KW - Janus Kinase 2 KW - Male KW - Middle Aged KW - Mutation KW - Precursor Cell Lymphoblastic Leukemia-Lymphoma KW - Prognosis KW - Receptors, Cytokine KW - Treatment Outcome KW - Tumor Suppressor Protein p53 TI - Mutations in TP53 and JAK2 are independent prognostic biomarkers in B-cell precursor acute lymphoblastic leukaemia. TY - research article VL - 117 ER -