RT Journal Article
T1 Scleredema developing after SARS-CoV-2 infection: a possible novel skin manifestation of coronavirus disease.
A1 Sanchez-Diaz, Manuel
A1 Lobato-Cano, Ruben
A1 Salvador-Rodriguez, Luis
A1 Lopez-Delgado, David
A1 Espadafor-Lopez, Beatriz
A1 Vilchez-Marquez, Francisco
A1 Ramos-Pleguezuelos, Francisco
A1 Molina-Leyva, Alejandro
A1 Arias-Santiago, Salvador
K1 SARS-CoV-2
K1 Humans
K1 Shoulder
K1 Skin Diseases
AB Scleredema is an uncommon sclerodermiform condition characterized by progressive thickening and hardening of the skin involving the neck, shoulders, proximal upper limbs and eventually the face. The diagnosis is based on the appearance of characteristic skin lesions and consistent histology [1]. Scleredema can be classified into three  subtypes (see supplementary table 1) [1-6]. The scientific evidence regarding its treatment is scarce and therapeutic guidelines are mainly based on expert opinion [6]. To the best of our knowledge, we report the first case of a patient with scleredema that appeared subsequent to COVID-19.A 47-year-old man had a history of obesity, COVID-19 from which he had recovered, and hepatitis B and C. He had no diabetes mellitus. After a positive SARS-CoV-2 PCR test, the patient presented with dyspnoea and fever. Complementary tests ruled out pneumonia, and he was discharged from the hospital. One week later, the patient improved and COVID-19-related symptoms disappeared.
PB John Libbey Eurotext
YR 2022
FD 2022
LK http://hdl.handle.net/10668/20453
UL http://hdl.handle.net/10668/20453
LA en
NO Sánchez-Díaz M, Lobato-Cano R, Salvador-Rodríguez L, Lopez-Delgado D, Espadafor-Lopez B, Vilchez-Marquez F, et al. Scleredema developing after SARS-CoV-2 infection: a possible novel skin manifestation of coronavirus disease. Eur J Dermatol. 2022 Feb 1;32(1):124-145.
DS RISalud
RD Apr 6, 2025