TY  - JOUR
AU  - Doello, Kevin
AU  - Mesas, Cristina
AU  - Quiñonero, Francisco
AU  - Perazzoli, Gloria
AU  - Cabeza, Laura
AU  - Prados, Jose
AU  - Melguizo, Consolacion
AU  - Ortiz, Raul
PY  - 2021
DO  - 10.3390/cancers13133169
UR  - http://hdl.handle.net/10668/4218
T2  - Cancers
AB  - Sodium selenite acts by depleting enzymes that protect against cellular oxidative stress. To determine its effect alone or in combination with gemcitabine (GMZ) in pancreatic cancer, we used PANC-1 and Pan02 cell lines and C57BL mice bearing a...
LA  - en
PB  - MDPI
KW  - Sodium selenite
KW  - Gemcitabine
KW  - Pancreatic cancer
KW  - Cancer stem cells
KW  - Combined therapy
KW  - Phospho-p38 protein
KW  - Selenito de sodio
KW  - Antineoplásicos
KW  - Neoplasias pancreáticas
KW  - Células madre neoplásicas
KW  - Tratamiento combinado
KW  - Anticuerpos
KW  - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans
KW  - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Rodentia::Muridae::Murinae::Mice
KW  - Medical Subject Headings::Organisms::Eukaryota::Animals
KW  - Medical Subject Headings::Chemicals and Drugs::Inorganic Chemicals::Sodium Compounds::Sodium Selenite
KW  - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Rodentia::Muridae::Murinae::Mice::Mice, Inbred Strains::Mice, Inbred C57BL
KW  - Medical Subject Headings::Chemicals and Drugs::Enzymes and Coenzymes::Enzymes::Oxidoreductases::NADH, NADPH Oxidoreductases::Apoptosis Inducing Factor
KW  - Medical Subject Headings::Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Survival
KW  - Medical Subject Headings::Phenomena and Processes::Metabolic Phenomena::Metabolism::Oxidative Stress
KW  - Medical Subject Headings::Diseases::Digestive System Diseases::Pancreatic Diseases::Pancreatic Neoplasms
KW  - Medical Subject Headings::Anatomy::Cells::Stem Cells::Neoplastic Stem Cells
KW  - Medical Subject Headings::Anatomy::Cells::Cells, Cultured::Cell Line::Cell Line, Tumor
TI  - The Antitumor Activity of Sodium Selenite Alone and in Combination with Gemcitabine in Pancreatic Cancer: An In Vitro and In Vivo Study
TY  - research article
ER  -