RT Journal Article
T1 Approach to the diagnosis of drug hypersensitivity reactions: similarities and differences between Europe and North America
A1 Torres, M J
A1 Romano, A
A1 Celik, G
A1 Demoly, P
A1 Khan, D A
A1 Macy, E
A1 Park, M
A1 Blumenthal, K
A1 Aberer, W
A1 Castells, M
A1 Barbaud, A
A1 Mayorga, C
A1 Bonadonna, P
K1 Drug
K1 Hypersensitivity
K1 Allergy
K1 Diagnosis
K1 Skin test
K1 In vitro test
K1 IgE
K1 T-cells
K1 Drug provocation test
K1 Sensitization
K1 Unit States
K1 Europe
AB Drug hypersensitivity reactions (DHRs) affect an unknown proportion of the general population, and are an important public health problem due to their potential to cause life-threatening anaphylaxis and rare severe cutaneous allergic reactions. DHR evaluations are frequently needed in both ambulatory and hospital settings and have a complex diagnosis that requires a detailed clinical history and other tests that may include in vitro tests and in vivo procedures such as skin tests and drug provocation tests. Although over the years both European and U.S. experts have published statements on general procedures for evaluating DHRs, a substantial discordance in their daily management exists. In this review, we highlight both the differences and the similarities between the European and U.S.
PB Biomed Central
YR 2017
FD 2017-03-13
LK http://hdl.handle.net/10668/2681
UL http://hdl.handle.net/10668/2681
LA en
NO Torres MJ, Romano A, Celik G, Demoly P, Khan DA, Macy E, et al.  Approach to the diagnosis of drug hypersensitivity reactions: similarities and differences between Europe and North America. Clin Transl Allergy. 2017; 13;7:7.
DS RISalud
RD Apr 18, 2025