TY - JOUR AU - Li, Fengjie AU - Janussen, Dorte AU - Peifer, Christian AU - PĂ©rez-Victoria, Ignacio AU - Tasdemir, Deniz PY - 2018 DO - 10.3390/md16080268 UR - http://hdl.handle.net/10668/12797 T2 - Marine drugs AB - The Antarctic deep-sea sponge Latrunculia (Latrunculia) biformis Kirkpatrick, 1908 (Class Demospongiae Sollas, Order Poecilosclerida Topsent, Latrunculiidae Topsent) was selected for chemical analyses due to its potent anticancer activity. Metabolomic... LA - en KW - Antarctica KW - Latrunculia, molecular networking KW - deep-sea KW - marine sponge KW - molecular docking KW - tsitsikammamine KW - Animals KW - Antineoplastic Agents KW - Cell Line, Tumor KW - DNA Topoisomerases, Type I KW - Doxorubicin KW - Humans KW - Keratinocytes KW - Models, Molecular KW - Molecular Structure KW - Porifera KW - Protein Conformation KW - Pyrroles KW - Quinolines TI - Targeted Isolation of Tsitsikammamines from the Antarctic Deep-Sea Sponge Latrunculia biformis by Molecular Networking and Anticancer Activity. TY - research article VL - 16 ER -