RT Journal Article T1 Complicated intra-abdominal infections worldwide: the definitive data of the CIAOW Study. A1 Sartelli, Massimo A1 Catena, Fausto A1 Ansaloni, Luca A1 Coccolini, Federico A1 Corbella, Davide A1 Moore, Ernest E A1 Malangoni, Mark A1 Velmahos, George A1 Coimbra, Raul A1 Koike, Kaoru A1 Leppaniemi, Ari A1 Biffl, Walter A1 Balogh, Zsolt A1 Bendinelli, Cino A1 Gupta, Sanjay A1 Kluger, Yoram A1 Agresta, Ferdinando A1 Di Saverio, Salomone A1 Tugnoli, Gregorio A1 Jovine, Elio A1 Ordonez, Carlos A A1 Whelan, James F A1 Fraga, Gustavo P A1 Gomes, Carlos Augusto A1 Pereira, Gerson Alves A1 Yuan, Kuo-Ching A1 Bala, Miklosh A1 Peev, Miroslav P A1 Ben-Ishay, Offir A1 Cui, Yunfeng A1 Marwah, Sanjay A1 Zachariah, Sanoop A1 Wani, Imtiaz A1 Rangarajan, Muthukumaran A1 Sakakushev, Boris A1 Kong, Victor A1 Ahmed, Adamu A1 Abbas, Ashraf A1 Gonsaga, Ricardo Alessandro Teixeira A1 Guercioni, Gianluca A1 Vettoretto, Nereo A1 Poiasina, Elia A1 Díaz-Nieto, Rafael A1 Massalou, Damien A1 Skrovina, Matej A1 Gerych, Ihor A1 Augustin, Goran A1 Kenig, Jakub A1 Khokha, Vladimir A1 Tranà, Cristian A1 Kok, Kenneth Yuh Yen A1 Mefire, Alain Chichom A1 Lee, Jae Gil A1 Hong, Suk-Kyung A1 Lohse, Helmut Alfredo Segovia A1 Ghnnam, Wagih A1 Verni, Alfredo A1 Lohsiriwat, Varut A1 Siribumrungwong, Boonying A1 El Zalabany, Tamer A1 Tavares, Alberto A1 Baiocchi, Gianluca A1 Das, Koray A1 Jarry, Julien A1 Zida, Maurice A1 Sato, Norio A1 Murata, Kiyoshi A1 Shoko, Tomohisa A1 Irahara, Takayuki A1 Hamedelneel, Ahmed O A1 Naidoo, Noel A1 Adesunkanmi, Abdul Rashid Kayode A1 Kobe, Yoshiro A1 Ishii, Wataru A1 Oka, Kazuyuki A1 Izawa, Yoshimitsu A1 Hamid, Hytham A1 Khan, Iqbal A1 Attri, Ak A1 Sharma, Rajeev A1 Sanjuán, Juan A1 Badiel, Marisol A1 Barnabé, Rita K1 Infecciones intraabdominales K1 Estudio multicéntrico K1 Absceso abdominal K1 Enfermedad crítica K1 Humanos K1 Drenaje K1 Procedimientos quirúrgicos del sistema digestivo K1 Farmacoresistencia microbiana K1 Reoperación K1 Infección hospitalaria K1 Adulto AB The CIAOW study (Complicated intra-abdominal infections worldwide observational study) is a multicenter observational study underwent in 68 medical institutions worldwide during a six-month study period (October 2012-March 2013). The study included patients older than 18 years undergoing surgery or interventional drainage to address complicated intra-abdominal infections (IAIs). 1898 patients with a mean age of 51.6 years (range 18-99) were enrolled in the study. 777 patients (41%) were women and 1,121 (59%) were men. Among these patients, 1,645 (86.7%) were affected by community-acquired IAIs while the remaining 253 (13.3%) suffered from healthcare-associated infections. Intraperitoneal specimens were collected from 1,190 (62.7%) of the enrolled patients. 827 patients (43.6%) were affected by generalized peritonitis while 1071 (56.4%) suffered from localized peritonitis or abscesses. The overall mortality rate was 10.5% (199/1898). According to stepwise multivariate analysis (PR = 0.005 and PE = 0.001), several criteria were found to be independent variables predictive of mortality, including patient age (OR = 1.1; 95%CI = 1.0-1.1; p < 0.0001), the presence of small bowel perforation (OR = 2.8; 95%CI = 1.5-5.3; p < 0.0001), a delayed initial intervention (a delay exceeding 24 hours) (OR = 1.8; 95%CI = 1.5-3.7; p < 0.0001), ICU admission (OR = 5.9; 95%CI = 3.6-9.5; p < 0.0001) and patient immunosuppression (OR = 3.8; 95%CI = 2.1-6.7; p < 0.0001). PB BioMed Central YR 2014 FD 2014-05-14 LK http://hdl.handle.net/10668/1798 UL http://hdl.handle.net/10668/1798 LA en NO Sartelli M, Catena F, Ansaloni L, Coccolini F, Corbella D, Moore EE, et al. Complicated intra-abdominal infections worldwide: the definitive data of the CIAOW Study. World Journal of Emergency Surgery. 2014; 9:37 NO Journal Article; DS RISalud RD Apr 5, 2025