%0 Journal Article
%A Sartelli, Massimo
%A Catena, Fausto
%A Ansaloni, Luca
%A Coccolini, Federico
%A Corbella, Davide
%A Moore, Ernest E
%A Malangoni, Mark
%A Velmahos, George
%A Coimbra, Raul
%A Koike, Kaoru
%A Leppaniemi, Ari
%A Biffl, Walter
%A Balogh, Zsolt
%A Bendinelli, Cino
%A Gupta, Sanjay
%A Kluger, Yoram
%A Agresta, Ferdinando
%A Di Saverio, Salomone
%A Tugnoli, Gregorio
%A Jovine, Elio
%A Ordonez, Carlos A
%A Whelan, James F
%A Fraga, Gustavo P
%A Gomes, Carlos Augusto
%A Pereira, Gerson Alves
%A Yuan, Kuo-Ching
%A Bala, Miklosh
%A Peev, Miroslav P
%A Ben-Ishay, Offir
%A Cui, Yunfeng
%A Marwah, Sanjay
%A Zachariah, Sanoop
%A Wani, Imtiaz
%A Rangarajan, Muthukumaran
%A Sakakushev, Boris
%A Kong, Victor
%A Ahmed, Adamu
%A Abbas, Ashraf
%A Gonsaga, Ricardo Alessandro Teixeira
%A Guercioni, Gianluca
%A Vettoretto, Nereo
%A Poiasina, Elia
%A Díaz-Nieto, Rafael
%A Massalou, Damien
%A Skrovina, Matej
%A Gerych, Ihor
%A Augustin, Goran
%A Kenig, Jakub
%A Khokha, Vladimir
%A Tranà, Cristian
%A Kok, Kenneth Yuh Yen
%A Mefire, Alain Chichom
%A Lee, Jae Gil
%A Hong, Suk-Kyung
%A Lohse, Helmut Alfredo Segovia
%A Ghnnam, Wagih
%A Verni, Alfredo
%A Lohsiriwat, Varut
%A Siribumrungwong, Boonying
%A El Zalabany, Tamer
%A Tavares, Alberto
%A Baiocchi, Gianluca
%A Das, Koray
%A Jarry, Julien
%A Zida, Maurice
%A Sato, Norio
%A Murata, Kiyoshi
%A Shoko, Tomohisa
%A Irahara, Takayuki
%A Hamedelneel, Ahmed O
%A Naidoo, Noel
%A Adesunkanmi, Abdul Rashid Kayode
%A Kobe, Yoshiro
%A Ishii, Wataru
%A Oka, Kazuyuki
%A Izawa, Yoshimitsu
%A Hamid, Hytham
%A Khan, Iqbal
%A Attri, Ak
%A Sharma, Rajeev
%A Sanjuán, Juan
%A Badiel, Marisol
%A Barnabé, Rita
%T Complicated intra-abdominal infections worldwide: the definitive data of the CIAOW Study.
%D 2014
%U http://hdl.handle.net/10668/1798
%X The CIAOW study (Complicated intra-abdominal infections worldwide observational study) is a multicenter observational study underwent in 68 medical institutions worldwide during a six-month study period (October 2012-March 2013). The study included patients older than 18 years undergoing surgery or interventional drainage to address complicated intra-abdominal infections (IAIs). 1898 patients with a mean age of 51.6 years (range 18-99) were enrolled in the study. 777 patients (41%) were women and 1,121 (59%) were men. Among these patients, 1,645 (86.7%) were affected by community-acquired IAIs while the remaining 253 (13.3%) suffered from healthcare-associated infections. Intraperitoneal specimens were collected from 1,190 (62.7%) of the enrolled patients. 827 patients (43.6%) were affected by generalized peritonitis while 1071 (56.4%) suffered from localized peritonitis or abscesses. The overall mortality rate was 10.5% (199/1898). According to stepwise multivariate analysis (PR = 0.005 and PE = 0.001), several criteria were found to be independent variables predictive of mortality, including patient age (OR = 1.1; 95%CI = 1.0-1.1; p < 0.0001), the presence of small bowel perforation (OR = 2.8; 95%CI = 1.5-5.3; p < 0.0001), a delayed initial intervention (a delay exceeding 24 hours) (OR = 1.8; 95%CI = 1.5-3.7; p < 0.0001), ICU admission (OR = 5.9; 95%CI = 3.6-9.5; p < 0.0001) and patient immunosuppression (OR = 3.8; 95%CI = 2.1-6.7; p < 0.0001).
%K Infecciones intraabdominales
%K Estudio multicéntrico
%K Absceso abdominal
%K Enfermedad crítica
%K Humanos
%K Drenaje
%K Procedimientos quirúrgicos del sistema digestivo
%K Farmacoresistencia microbiana
%K Reoperación
%K Infección hospitalaria
%K Adulto
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