TY  - JOUR
AU  - Garrido, Federico
AU  - Aptsiauri, Natalia
AU  - Doorduijn, Elien M
AU  - Garcia Lora, Angel M
AU  - van Hall, Thorbald
PY  - 2016
DO  - 10.1016/j.coi.2015.12.007
SN  - 0952-7915
UR  - http://hdl.handle.net/10668/2236
T2  - Current Opinion in Immunology
AB  - Immune escape strategies aimed to avoid T-cell recognition, including the loss of tumor MHC class I expression, are commonly found in malignant cells. Tumor immune escape has proven to have a negative effect on the clinical outcome of cancer...
LA  - en
PB  - Elsevier
KW  - Presentación de antígeno
KW  - Genes clase I del complejo de histocompatibilidad (MHC)
KW  - Antígenos de histocompatibilidad clase I
KW  - Humanos
KW  - Inmunoterapia
KW  - Neoplasias
KW  - Linfocitos T
KW  - Escape del tumor
KW  - Regulación hacia arriba
KW  - Medical Subject Headings::Phenomena and Processes::Immune System Phenomena::Immune System Processes::Antigen Presentation
KW  - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Structures::Genome::Genome Components::Genes::Major Histocompatibility Complex::Genes, MHC Class I
KW  - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Glycoproteins::Membrane Glycoproteins::Histocompatibility Antigens Class I
KW  - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans
KW  - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Therapeutics::Biological Therapy::Immunomodulation::Immunotherapy
KW  - Medical Subject Headings::Diseases::Neoplasms
KW  - Medical Subject Headings::Anatomy::Cells::Blood Cells::Leukocytes::Leukocytes, Mononuclear::Lymphocytes::T-Lymphocytes
KW  - Medical Subject Headings::Phenomena and Processes::Immune System Phenomena::Immune System Processes::Tumor Escape
KW  - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Processes::Gene Expression Regulation::Up-Regulation
TI  - The urgent need to recover MHC class I in cancers for effective immunotherapy.
TY  - research article
ER  -