%0 Journal Article
%A Carrasco Hernández, Laura
%A Caballero Eraso, Candela
%A Ruiz-Duque, Borja
%A Abad Arranz, María
%A Márquez Martín, Eduardo
%A Calero Acuña, Carmen
%A Lopez-Campos, Jose Luis
%T Predictors of Single Bronchodilation Treatment Response for COPD: An Observational Study with the Trace Database Cohort.
%D 2021
%@ 2077-0383
%U https://hdl.handle.net/10668/27503
%X Chronic obstructive pulmonary disease (COPD) patients constitute a heterogeneous population in terms of treatment response. Our objective was to identify possible predictive factors of response to treatment with single bronchodilation monotherapy in patients diagnosed with COPD. The Time-based Register and Analysis of COPD Endpoints (TRACE  clinicaltrials.gov NCT03485690) is a prospective cohort of COPD patients who have been attending annual visits since 2012. Patients who were kept on a single bronchodilator during the first year of follow-up were selected. The responders were defined according to all of the following variables: any improvement in morning post-dose forced expiratory volume in 1 s or deterioration
%K COPD
%K clinical response
%K long-acting bronchodilators
%K pharmacological
%~