%0 Journal Article
%A Araque Arroyo, Patricia
%A Ubago Perez, Ruth
%A Fernandez Feijoo, Maria Amalia
%A Calleja Hernandez, Miguel Angel
%T Good clinical and cost outcomes using dexrazoxane to treat accidental epirubicin extravasation
%D 2011
%@ 0973-1482
%U http://hdl.handle.net/10668/554
%X A 75-year-old man diagnosed with lower esophageal adenocarcinoma suffered from epirubicin extravasation during the second cycle of neoadjuvant chemotherapy with epirubicin and oxaliplatin. A full recovery was achieved after treatment with dexrazoxane (Cardioxane® ). This is the first time in our hospital that extravasation of an anthracycline has been treated with dexrazoxane. We used Cardioxane® , approved for the prevention of anthracycline-induced cardiotoxicity, while Savene® is indicated for the treatment of anthracycline extravasation. The treatment was effective, and the selection of Cardioxane® (seven-fold cheaper than Savene® ) yielded a cost saving. Consequently, Cardioxane® has been included in our guidelines for anthracycline extravasation.
%K Anciano
%K Antineoplásicos
%K Análisis Costo-Beneficio
%K Epirrubicina
%K Extravasación de Materiales Terapéuticos y Diagnósticos
%K Humanos
%K Masculino
%K Razoxano
%K Resultado del Tratamiento
%K Anthracycline
%K Chemotherapy
%K cost
%K Desraxozane
%K extravasation
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