TY  - JOUR
AU  - López-Nevado, Marta
AU  - González-Granado, Luis I.
AU  - Ruiz-García, Raquel
AU  - Pleguezuelo, Daniel
AU  - Cabrera-Marante, Oscar
AU  - Salmón, Nerea
AU  - Blanco-Lobo, Pilar
AU  - Domínguez-Pinilla, Nerea
AU  - Rodríguez-Pena, Rebeca
AU  - Sebastián, Elena
AU  - Cruz-Rojo, Jaime
AU  - Olbrich, Peter
AU  - Ruiz-Contreras, Jesús
AU  - Paz-Artal, Estela
AU  - Neth, Olaf
AU  - Allende, Luis M.
PY  - 2021
DO  - 10.3389/fimmu.2021.671755
UR  - http://hdl.handle.net/10668/3632
T2  - Frontiers in Immunology
AB  - Primary immune regulatory disorders (PIRD) are associated with autoimmunity, autoinflammation and/or dysregulation of lymphocyte homeostasis. Autoimmune lymphoproliferative syndrome (ALPS) is a PIRD due to an apoptotic defect in Fas-FasL pathway and...
LA  - en
PB  - Frontiers
KW  - ALPS
KW  - ALPS-like
KW  - Autoimmunity
KW  - Lymphoproliferation
KW  - Malignancy
KW  - Immune dysregulation
KW  - Síndrome linfoproliferativo autoinmune
KW  - Autoinmunidad
KW  - Medical Subject Headings::Diseases::Hemic and Lymphatic Diseases::Lymphatic Diseases::Lymphoproliferative Disorders::Autoimmune Lymphoproliferative Syndrome
KW  - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Early Diagnosis
KW  - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans
KW  - Medical Subject Headings::Chemicals and Drugs::Biological Factors::Antigens::Antigens, Surface::Antigens, Differentiation::Antigens, Differentiation, T-Lymphocyte::CTLA-4 Antigen
KW  - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Membrane Proteins::Receptors, Cell Surface::Receptors, Immunologic::Receptors, Natural Killer Cell::Receptors, NK Cell Lectin-Like::NK Cell Lectin-Like...
KW  - Medical Subject Headings::Phenomena and Processes::Immune System Phenomena::Immunity::Autoimmunity
KW  - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Diagnostic Techniques and Procedures::Monitoring, Physiologic
TI  - Primary Immune Regulatory Disorders With an Autoimmune Lymphoproliferative Syndrome-Like Phenotype: Immunologic Evaluation, Early Diagnosis and Management
TY  - research article
ER  -