TY  - GEN
AU  - Lorenzo, Petra I.
AU  - Juarez-Vicente, Francisco
AU  - Cobo-Vuilleumier, Nadia
AU  - Garcia-Dominguez, Mario
AU  - Gauthier, Benoit R.
PY  - 2017
DO  - 10.3390/genes8030101
SN  - 2073-4425
UR  - http://hdl.handle.net/10668/19260
T2  - Genes
AB  - Paired box 4 (PAX4) is a key factor in the generation of insulin producing beta-cells during embryonic development. In adult islets, PAX4 expression is sequestered to a subset of beta-cells that are prone to proliferation and more resistant to...
LA  - en
PB  - Mdpi
KW  - PAX4
KW  - transcription regulation
KW  - SUMOylation
KW  - diabetes mellitus
KW  - beta-cell adaptation
KW  - regenerative therapy
KW  - Paired domain
KW  - Dna-binding
KW  - Sequence recognition
KW  - Stem-cells
KW  - Endocrine progenitors
KW  - Messenger-rna
KW  - Beta-cells
KW  - Expression
KW  - Differentiation
KW  - Repressor
TI  - The Diabetes-Linked Transcription Factor PAX4: From Gene to Functional Consequences
TY  - review
VL  - 8
ER  -