TY  - JOUR
AU  - Ortiz, Raúl
AU  - Prados, José
AU  - Melguizo, Consolación
AU  - Arias, José L
AU  - Ruiz, M Adolfina
AU  - Alvarez, Pablo J
AU  - Caba, Octavio
AU  - Luque, Raquel
AU  - Segura, Ana
AU  - Aránega, Antonia
PY  - 2012
DO  - 10.2147/IJN.S26401
SN  - 1176-9114
UR  - http://hdl.handle.net/10668/569
T2  - International journal of nanomedicine
AB  - This work aimed to develop a new therapeutic approach to increase the efficacy of 5-fluorouracil (5-FU) in the treatment of advanced or recurrent colon cancer. 5-FU-loaded biodegradable poly(ε-caprolactone) nanoparticles (PCL NPs) were combined with...
LA  - en
PB  - Dove Medical Press
KW  - colon cancer
KW  - combined therapy
KW  - 5-fluorouracil
KW  - gene therapy
KW  - E gene
KW  - poly (ε-caprolactone)
KW  - Neoplasias del Colon
KW  - Terapia de Gen
KW  - Humanos
KW  - Fluorouracilo
KW  - Nanopartículas
KW  - Antineoplásicos
KW  - Apoptosis
KW  - Medical Subject Headings::Diseases::Neoplasms::Neoplasms by Site::Digestive System Neoplasms::Gastrointestinal Neoplasms::Intestinal Neoplasms::Colorectal Neoplasms::Colonic Neoplasms
KW  - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Therapeutics::Biological Therapy::Gene Therapy
KW  - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans
KW  - Medical Subject Headings::Chemicals and Drugs::Heterocyclic Compounds::Heterocyclic Compounds, 1-Ring::Pyrimidines::Pyrimidinones::Uracil::Fluorouracil
KW  - Medical Subject Headings::Technology, Industry, Agriculture::Technology, Industry, and Agriculture::Manufactured Materials::Nanostructures::Nanoparticles
KW  - Medical Subject Headings::Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Therapeutic Uses::Antineoplastic Agents
TI  - 5-Fluorouracil-loaded poly(ε-caprolactone) nanoparticles combined with phage E gene therapy as a new strategy against colon cancer
TY  - research article
ER  -