TY - JOUR AU - Lopez-Grueso, Maria Jose AU - Lagal, Daniel Jose AU - Garcia-Jimenez, Alvaro Fernando AU - Tarradas, Rosa Maria AU - Carmona-Hidalgo, Beatriz AU - Peinado, Jose AU - Requejo-Aguilar, Raquel AU - Barcena, Jose Antonio AU - Padilla, Carmen Alicia PY - 2020 DO - 10.1016/j.redox.2020.101737 UR - http://hdl.handle.net/10668/16387 T2 - Redox biology AB - Peroxiredoxin 6 (PRDX6) has been associated with tumor progression and cancer metastasis. Its acting on phospholipid hydroperoxides and its phospholipase-A2 activity are unique among the peroxiredoxin family and add complexity to its action... LA - en PB - Elsevier KW - CRISPR-Cas9 KW - Carbohydrate metabolism KW - Cell cycle KW - Glucose metabolism KW - Lipokines KW - Mitochondria KW - NRF2 KW - PCNA KW - Peroxiredoxin 6 KW - Proteomics KW - Redox proteome KW - 3-Phosphoinositide-dependent protein kinases KW - Cell cycle checkpoints KW - Hep G2 cells KW - Humans KW - Mitochondria KW - Oxidation-reduction KW - Peroxiredoxin VI KW - Reactive oxygen species TI - Knockout of PRDX6 induces mitochondrial dysfunction and cell cycle arrest at G2/M in HepG2 hepatocarcinoma cells. TY - research article VL - 37 ER -