RT Journal Article
T1 Celiac Disease Autoimmunity.
A1 López Casado, Miguel Ángel
A1 Lorite, Pedro
A1 Ponce de León, Candelaria
A1 Palomeque, Teresa
A1 Torres, Maria Isabel
K1 Autoantibodies
K1 Autoimmunity
K1 Celiac disease
K1 Immune tolerance
AB Celiac disease is an autoimmune condition triggered by the ingestion of gluten, the protein fraction of wheat, barley and rye. It is not simply an intestinal disease; it is multifactorial caused by many different genetic factors acting together with non-genetic causes. Similar to other autoimmune diseases, celiac disease is a polygenic disorder for which the major histocompatibility complex locus is the most important genetic factor, and is the result of an immune response to self-antigens leading to tissue destruction and the autoantibodies production. Celiac disease exemplifies how an illness can have autoimmune-like features having to be driven by exogenous antigen and how can be reasonably considered as a model of organ-specific autoimmunity.
YR 2018
FD 2018-08-25
LK http://hdl.handle.net/10668/12887
UL http://hdl.handle.net/10668/12887
LA en
DS RISalud
RD Apr 9, 2025