%0 Journal Article
%A López Casado, Miguel Ángel
%A Lorite, Pedro
%A Ponce de León, Candelaria
%A Palomeque, Teresa
%A Torres, Maria Isabel
%T Celiac Disease Autoimmunity.
%D 2018
%U http://hdl.handle.net/10668/12887
%X Celiac disease is an autoimmune condition triggered by the ingestion of gluten, the protein fraction of wheat, barley and rye. It is not simply an intestinal disease; it is multifactorial caused by many different genetic factors acting together with non-genetic causes. Similar to other autoimmune diseases, celiac disease is a polygenic disorder for which the major histocompatibility complex locus is the most important genetic factor, and is the result of an immune response to self-antigens leading to tissue destruction and the autoantibodies production. Celiac disease exemplifies how an illness can have autoimmune-like features having to be driven by exogenous antigen and how can be reasonably considered as a model of organ-specific autoimmunity.
%K Autoantibodies
%K Autoimmunity
%K Celiac disease
%K Immune tolerance
%~