TY - JOUR AU - Guerrero, Fatima AU - Carmona, Andres AU - Jimenez, Maria Jose AU - Obrero, Teresa AU - Pulido, Victoria AU - Moreno, Juan Antonio AU - Soriano, Sagrario AU - Martin-Malo, Alejandro AU - Aljama, Pedro PY - 2021 DO - 10.3390/toxins13100738 UR - https://hdl.handle.net/10668/25865 T2 - Toxins AB - Endothelial aging may be induced early in pathological situations. The uremic toxins indoxyl sulfate (IS) and p-cresol (PC) accumulate in the plasma of chronic kidney disease (CKD) patients, causing accelerated endothelial aging, increased... LA - en PB - Mdpi KW - aging KW - indoxyl sulfate KW - p-cresol KW - endothelial cells KW - endothelial dysfunction KW - senescence KW - Smooth-muscle-cells KW - Indoxyl sulfate KW - P-cresol KW - Stress KW - Proliferation KW - Disease TI - Passage Number-Induced Replicative Senescence Modulates the Endothelial Cell Response to Protein-Bound Uremic Toxins TY - research article VL - 13 ER -