TY  - JOUR
AU  - Quiñones, Mar
AU  - Al-Massadi, Omar
AU  - Folgueira, Cintia
AU  - Bremser, Stephan
AU  - Gallego, Rosalia
AU  - Torres-Leal, Leonardo
AU  - Haddad-Tovolli, Roberta
AU  - Garcia-Caceres, Cristina
AU  - Hernandez-Bautista, Rene
AU  - Lam, Brian Y H
AU  - Beiroa, Daniel
AU  - Sanchez-Rebordelo, Estrella
AU  - Senra, Ana
AU  - Malagon, Jose A
AU  - Valerio, Patricia
AU  - Fondevila, Marcos F
AU  - Fernø, Johan
AU  - Malagon, Maria M
AU  - Contreras, Raian
AU  - Pfluger, Paul
AU  - Brüning, Jens C
AU  - Yeo, Giles
AU  - Tschöp, Matthias
AU  - Dieguez, Carlos
AU  - Lopez, Miguel
AU  - Claret, Marc
AU  - Kloppenburg, Peter
AU  - Sabio, Guadalupe
AU  - Nogueiras, Ruben
PY  - 2018
DO  - 10.1038/s41467-018-05711-6
UR  - http://hdl.handle.net/10668/12869
T2  - Nature communications
AB  - p53 is a well-known tumor suppressor that has emerged as an important player in energy balance. However, its metabolic role in the hypothalamus remains unknown. Herein, we show that mice lacking p53 in agouti-related peptide (AgRP), but not...
LA  - en
PB  - Nature Publishing Group
KW  - Adipose tissue, brown
KW  - Agouti-related protein
KW  - Animals
KW  - Diet
KW  - Hypothalamus
KW  - Male
KW  - Mice
KW  - Mice, inbred C57BL
KW  - Mitogen-activated protein kinase 8
KW  - Neurons
KW  - Obesity
KW  - Pro-opiomelanocortin
KW  - Rats, sprague-dawley
KW  - Steroidogenic factor 1
KW  - Tumor suppressor protein p53
TI  - p53 in AgRP neurons is required for protection against diet-induced obesity via JNK1.
TY  - research article
VL  - 9
ER  -