TY - JOUR AU - Mora-Molina, Rocío AU - Stöhr, Daniela AU - Rehm, Markus AU - López-Rivas, Abelardo PY - 2022 DO - 10.1038/s41419-022-04574-6 UR - http://hdl.handle.net/10668/19526 T2 - Cell death & disease AB - Protein misfolding or unfolding and the resulting endoplasmic reticulum (ER) stress frequently occur in highly proliferative tumors. How tumor cells escape cell death by apoptosis after chronic ER stress remains poorly understood. We have investigated... LA - en KW - Apoptosis KW - CASP8 and FADD-Like Apoptosis Regulating Protein KW - Cell Line, Tumor KW - Colonic Neoplasms KW - Down-Regulation KW - Endoplasmic Reticulum Stress KW - Humans KW - TNF-Related Apoptosis-Inducing Ligand KW - Tumor Microenvironment TI - cFLIP downregulation is an early event required for endoplasmic reticulum stress-induced apoptosis in tumor cells. TY - research article VL - 13 ER -