TY - JOUR AU - Carrillo-Gálvez, Ana Belén AU - Gálvez-Peisl, Sheyla AU - González-Correa, Juan Elías AU - de Haro-Carrillo, Marina AU - Ayllón, Verónica AU - Carmona-Sáez, Pedro AU - Ramos-Mejía, Verónica AU - Galindo-Moreno, Pablo AU - Cara, Francisca E. AU - Granados-Principal, Sergio AU - Muñoz, Pilar AU - Martin, Francisco AU - Anderson, Per PY - 2020 DO - 10.1002/sctm.19-0372 SN - 2157-6564 UR - http://hdl.handle.net/10668/3512 T2 - Stem Cells Translational Medicine AB - Multipotent mesenchymal stromal cells (MSCs) have emerged as a promising cell therapy in regenerative medicine and for autoimmune/inflammatory diseases. However, a main hurdle for MSCs-based therapies is the loss of their proliferative potential in... LA - en PB - Wiley Periodicals, Inc. on behalf of AlphaMed Press KW - DNA damage KW - Mesenchymal stromal cells (MSCs) KW - Proliferation KW - ROS KW - TGF-β KW - Daño del ADN KW - Células madre mesenquimatosas KW - Proliferación celular KW - Especies reactivas de oxígeno KW - Factor de crecimiento transformador beta KW - Medical Subject Headings::Organisms::Eukaryota::Animals KW - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans KW - Medical Subject Headings::Anatomy::Cells::Stem Cells::Multipotent Stem Cells::Mesenchymal Stromal Cells KW - Medical Subject Headings::Anatomy::Cells::Cellular Structures::Intracellular Space::Cytoplasm::Cytoplasmic Structures::Organelles::Mitochondria KW - Medical Subject Headings::Chemicals and Drugs::Inorganic Chemicals::Free Radicals::Reactive Oxygen Species KW - Medical Subject Headings::Chemicals and Drugs::Biological Factors::Intercellular Signaling Peptides and Proteins::Transforming Growth Factors::Transforming Growth Factor beta TI - GARP is a key molecule for mesenchymal stromal cell responses to TGF-β and fundamental to control mitochondrial ROS levels TY - research article ER -