RT Journal Article
T1 Liquid Biopsy as a Tool for the Characterisation and Early Detection of the Field Cancerization Effect in Patients with Oral Cavity Carcinoma
A1 Pérez-Ruiz, Elisabeth
A1 Gutiérrez, Vanesa
A1 Muñoz, Marta
A1 Oliver, Javier
A1 Sánchez, Marta
A1 Gálvez-Carvajal, Laura
A1 Rueda-Domínguez, Antonio
A1 Barragán, Isabel
K1 Oral cell carcinoma
K1 Field cancerization
K1 Liquid biopsy
K1 Tobacco
K1 Saliva
K1 Early diagnosis
K1 Carcinoma de células escamosas de cabeza y cuello
K1 Biopsia líquida
K1 Tabaco
K1 Diagnóstico precoz
K1 Detección precoz del cáncer
AB Oral squamous cell carcinoma (OSCC) constitutes approximately 25% of all head and neck cancer, for which the consumption of tobacco and alcohol are the main associated risk factors. The field cancerization effect of OSCC is one of the main reasons for the poor survival rates associated with this disease. Despite some advances, its ccharacterization and early diagnosis continue to challenge modern oncology, and the goal of improving the prognosis remains to be achieved. Among new early diagnostic tools for OSCC that have been proposed, liquid biopsy appears to be an ideal candidate, as studies have shown that the analysis of blood and saliva provides promising data for the early detection of relapses or second tumours.
PB MDPI
YR 2021
FD 2021-10-15
LK http://hdl.handle.net/10668/4333
UL http://hdl.handle.net/10668/4333
LA en
NO Pérez-Ruiz E, Gutiérrez V, Muñoz M, Oliver J, Sánchez M, Gálvez-Carvajal L, et al. Liquid Biopsy as a Tool for the Characterisation and Early Detection of the Field Cancerization Effect in Patients with Oral Cavity Carcinoma. Biomedicines. 2021 Oct 15;9(10):1478
DS RISalud
RD Apr 7, 2025