TY  - JOUR
AU  - Forstner, Andreas J.
AU  - Fischer, Sascha B.
AU  - Schenk, Lorena M.
AU  - Strohmaier, Jana
AU  - Maaser-Hecker, Anna
AU  - Reinbold, Céline S.
AU  - Sivalingam, Sugirthan
AU  - Hecker, Julian
AU  - Streit, Fabian
AU  - Degenhardt, Franziska
AU  - Witt, Stephanie H.
AU  - Schumacher, Johannes
AU  - Thiele, Holger
AU  - Nürnberg, Peter
AU  - Guzman-Parra, José
AU  - Orozco Diaz, Guillermo
AU  - Auburger, Georg
AU  - Albus, Margot
AU  - Borrmann-Hassenbach, Margitta
AU  - González, Maria José
AU  - Gil Flores, Susana
AU  - Cabaleiro Fabeiro, Francisco J.
AU  - del Río Noriega, Francisco
AU  - Perez Perez, Fermin
AU  - Haro González, Jesus
AU  - Rivas, Fabio
AU  - Mayoral, Fermin
AU  - Bauer, Michael
AU  - Pfennig, Andrea
AU  - Reif, Andreas
AU  - Herms, Stefan
AU  - Hoffmann, Per
AU  - Pirooznia, Mehdi
AU  - Goes, Fernando S.
AU  - Rietschel, Marcella
AU  - Nöthen, Markus M.
AU  - Cichon, Sven
PY  - 2020
DO  - 10.1038/s41398-020-0732-y
UR  - http://hdl.handle.net/10668/3860
T2  - Translational Psychiatry
AB  - Bipolar disorder (BD) is a highly heritable neuropsychiatric disease characterized by recurrent episodes of depression and mania. Research suggests that the cumulative impact of common alleles explains 25-38% of phenotypic variance, and that rare...
LA  - en
PB  - Springer Nature
KW  - Whole exome sequencing
KW  - Bipolar disorder
KW  - Neuropsychiatry
KW  - Genetic predisposition to disease
KW  - Secuenciación del exoma completo
KW  - Trastorno bipolar
KW  - Neuropsiquiatría
KW  - Predisposición genética a la enfermedad
KW  - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Structures::Genome::Exome
KW  - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genotype::Genetic Predisposition to Disease
KW  - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans
KW  - Medical Subject Headings::Psychiatry and Psychology::Mental Disorders::Schizophrenia and Disorders with Psychotic Features::Schizophrenia
KW  - Medical Subject Headings::Psychiatry and Psychology::Mental Disorders::Mood Disorders::Affective Disorders, Psychotic::Bipolar Disorder
KW  - Medical Subject Headings::Psychiatry and Psychology::Mental Disorders::Mental Disorders Diagnosed in Childhood::Child Development Disorders, Pervasive::Autistic Disorder
KW  - Medical Subject Headings::Geographical Locations::Geographic Locations::Europe::Spain
KW  - Medical Subject Headings::Geographical Locations::Geographic Locations::Europe::Germany
KW  - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Inheritance Patterns::Penetrance
KW  - Medical Subject Headings::Anatomy::Nervous System::Central Nervous System::Brain
TI  - Whole-exome sequencing of 81 individuals from 27 multiply affected bipolar disorder families
TY  - research article
ER  -