TY  - JOUR
AU  - Ortega, Francisco J
AU  - Moreno-Navarrete, José M
AU  - Mayas Torres, María Dolores
AU  - García-Santos, Eva
AU  - Gómez-Serrano, María
AU  - Rodríguez-Hermosa, José I
AU  - Ruiz, Bartomeu
AU  - Ricart, Wifredo
AU  - Tinahones, Francisco J
AU  - Frühbeck, Gema
AU  - Peral, Belén
AU  - Fernández-Real, José M
PY  - 2012
DO  - 10.1371/journal.pone.0033233
UR  - http://hdl.handle.net/10668/663
T2  - PloS one
AB  - CONTEXTExpression and activity of the main lipogenic enzymes is paradoxically decreased in obesity, but the mechanisms behind these findings are poorly known. Breast Cancer 1 (BrCa1) interacts with acetyl-CoA carboxylase (ACC) reducing the rate of...
LA  - en
PB  - Public Library of Science
KW  - RNA, Messenger
KW  - Acetyl-CoA Carboxylase
KW  - BRCA1 Protein
KW  - ARN Mensajero
KW  - Acetil CoA Carboxilasa
KW  - Proteína BRCA1
KW  - Adipocitos
KW  - Tejido Adiposo
KW  - Diferenciación Celular
KW  - Lipogénesis
KW  - Macrófagos
KW  - Obesidad
KW  - Fosforilación oxidativa
KW  - Células 3T3-L1
KW  - Medical Subject Headings::Chemicals and Drugs::Enzymes and Coenzymes::Enzymes::Ligases::Carbon-Carbon Ligases::Acetyl-CoA Carboxylase
KW  - Medical Subject Headings::Anatomy::Cells::Connective Tissue Cells::Adipocytes
KW  - Medical Subject Headings::Anatomy::Tissues::Connective Tissue::Adipose Tissue
KW  - Medical Subject Headings::Named Groups::Persons::Age Groups::Adult
KW  - Medical Subject Headings::Organisms::Eukaryota::Animals
KW  - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Neoplasm Proteins::Tumor Suppressor Proteins::BRCA1 Protein
KW  - Medical Subject Headings::Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Differentiation
KW  - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans
KW  - Medical Subject Headings::Phenomena and Processes::Chemical Phenomena::Biochemical Phenomena::Biochemical Processes::Lipogenesis
KW  - Medical Subject Headings::Anatomy::Cells::Connective Tissue Cells::Macrophages
KW  - Medical Subject Headings::Check Tags::Male
KW  - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Rodentia::Muridae::Murinae::Mice
KW  - Medical Subject Headings::Diseases::Nutritional and Metabolic Diseases::Nutrition Disorders::Overnutrition::Obesity
KW  - Medical Subject Headings::Phenomena and Processes::Chemical Phenomena::Biochemical Phenomena::Biochemical Processes::Phosphorylation::Oxidative Phosphorylation
KW  - Medical Subject Headings::Chemicals and Drugs::Nucleic Acids, Nucleotides, and Nucleosides::Nucleic Acids::RNA::RNA, Messenger
KW  - Medical Subject Headings::Anatomy::Cells::Cells, Cultured::Cell Line::3T3 Cells::Swiss 3T3 Cells::3T3-L1 Cells
TI  - Breast cancer 1 (BrCa1) may be behind decreased lipogenesis in adipose tissue from obese subjects.
TY  - research article
ER  -