RT Journal Article T1 Differences Between Takotsubo and the Working Diagnosis of Myocardial Infarction With Nonobstructive Coronary Arteries. A1 Lopez-Pais, Javier A1 Izquierdo Coronel, Bárbara A1 Raposeiras-Roubín, Sergio A1 Álvarez Rodriguez, Leyre A1 Vedia, Oscar A1 Almendro-Delia, Manuel A1 Sionis, Alessandro A1 Martin-Garcia, Agustin C A1 Uribarri, Aitor A1 Blanco, Emilia A1 Martín de Miguel, Irene A1 Abu-Assi, Emad A1 Galán Gil, David A1 Sestayo Fernández, Manuela A1 Espinosa Pascual, Maria Jesús A1 Agra-Bermejo, Rosa María A1 López Otero, Diego A1 García Acuña, Jose María A1 Alonso Martín, Joaquín Jesús A1 Gonzalez-Juanatey, Jose Ramón A1 Perez de Juan Romero, Miguel Ángel A1 Núñez-Gil, Iván J K1 MINOCA K1 Takotsubo K1 definition K1 prognosis K1 working diagnosis AB Whether Takotsubo syndrome (TTS) should be classified within myocardial infarction with non-obstructive coronary arteries (MINOCAs) is still controversial. The aim of this work was to evaluate the main differences between TTS and non-TTS MINOCAs. A cohort study based on two prospective registries: TTS from the RETAKO registry (N:1,015) and patients with non-TTS MINOCAs from contemporary records of acute myocardial infarction from five 5 national centers (N:1,080). Definitions and management recommended by the ESC were used. Survival analysis was based on the Cox regression analysis; propensity score matching (PS) was created to adjust prognostic variables. Takotsubo syndrome were more often women (85.9 vs. 51.9%; p Compared to the rest of MINOCAs, TTS presents a different patient profile and a more aggressive acute phase. However, its long-term cardiovascular prognosis is better. These results support that TTS should be considered a separate entity with unique characteristics and prognosis. SN 2297-055X YR 2022 FD 2022-03-14 LK http://hdl.handle.net/10668/20543 UL http://hdl.handle.net/10668/20543 LA en DS RISalud RD Apr 5, 2025