TY - JOUR AU - Muñoz-Galván, Sandra AU - Rivero, Maria AU - Peinado-Serrano, Javier AU - Martinez-Pérez, Julia AU - Fernández-Fernández, M C AU - Ortiz, María José AU - García-Heredia, José M AU - Carnero, Amancio PY - 2020 DO - 10.3390/cells9051071 UR - http://hdl.handle.net/10668/15454 T2 - Cells AB - Colorectal cancer (CRC) is the third most common cancer worldwide. The standard treatment in locally advanced rectal cancer is preoperative radiation alone or in combination with chemotherapy, followed by adjuvant chemotherapy. Rectal cancer is highly... LA - en KW - PAI-1/Serpin E-1 KW - Pim kinases KW - chemoresistance KW - rectal cancer KW - therapy KW - Adult KW - Aged KW - Apoptosis KW - Biomarkers, Pharmacological KW - Biomarkers, Tumor KW - Biphenyl Compounds KW - Cell Line, Tumor KW - Cell Proliferation KW - Cell Survival KW - Colorectal Neoplasms KW - Female KW - Humans KW - Male KW - Middle Aged KW - Neoplasm Recurrence, Local KW - Plasminogen Activator Inhibitor 1 KW - Prognosis KW - Protein Kinase Inhibitors KW - Protein Serine-Threonine Kinases KW - Rectal Neoplasms KW - Thiazolidines TI - PAI1 is a Marker of Bad Prognosis in Rectal Cancer but Predicts a Better Response to Treatment with PIM Inhibitor AZD1208. TY - research article VL - 9 ER -