TY - JOUR AU - Lopez-Gambero, Antonio J AU - Pacheco-Sanchez, Beatriz AU - Rosell-Valle, Cristina AU - Medina-Vera, Dina AU - Navarro, Juan Antonio AU - Fernandez-Arjona, Maria Del Mar AU - de-Ceglia, Marialuisa AU - Sanjuan, Carlos AU - Simon, Vincent AU - Cota, Daniela AU - Rivera, Patricia AU - Rodriguez-de-Fonseca, Fernando AU - Suarez, Juan PY - 2022 DO - 10.1016/j.biopha.2022.112994 UR - http://hdl.handle.net/10668/22043 T2 - Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie AB - Increasing evidence shows that hypothalamic dysfunction, insulin resistance, and weight loss precede and progress along with the cognitive decline in sporadic Alzheimer's Disease (AD) with sex differences. This study aimed to determine the effect of... LA - en PB - Elsevier KW - Alzheimer’s disease KW - D-chiro-inositol KW - Fatty liver disease KW - Hypothalamus KW - Inflammation KW - Insulin signaling KW - Alzheimer Disease KW - Animals KW - Disease Models, Animal KW - Female KW - Humans KW - Inositol KW - Insulin KW - Insulin Resistance KW - Male KW - Mice KW - Mice, Transgenic KW - Weight Loss TI - Dietary administration of D-chiro-inositol attenuates sex-specific metabolic imbalances in the 5xFAD mouse model of Alzheimer's disease. TY - research article VL - 150 ER -