RT Journal Article
T1 Anti-Inflammatory Effects of the Mediterranean Diet in the Early and Late Stages of Atheroma Plaque Development
A1 Casas, Rosa
A1 Urpi-Sarda, Mireia
A1 Sacanella, Emilio
A1 Arranz, Sara
A1 Corella, Dolores
A1 Castaner, Olga
A1 Lamuela-Raventos, Rosa-Maria
A1 Salas-Salvado, Jordi
A1 Lapetra, Jose
A1 Portillo, Maria P.
A1 Estruch, Ramon
K1 Low-grade inflammation
K1 Cardiovascular-disease
K1 High-risk
K1 Markers
K1 Atherosclerosis
K1 Activation
K1 Cytokines
K1 Pattern
AB Objective. To evaluate the long-term effects of a Mediterranean diet (MeDiet) intervention on the plasma concentrations of inflammatory and plaque stability-related molecules in elderly people at high risk for cardiovascular disease. Design and Setting. 66 participants from primary care centers affiliated with the Hospital Clinic of Barcelona were randomized into 3 groups: MeDiet plus extra virgin olive oil (EVOO) or nuts and a low-fat diet (LFD). At baseline and at 3 and 5 years, we evaluated the changes in the plasma concentrations of 24 inflammatory biomarkers related to the different stages of the atherosclerotic process by Luminex (R). Results. At 3 and 5 years, both MeDiet groups showed a significant reduction of IL-6, IL-8, MCP-1, and MIP-1 beta (P
PB Hindawi ltd
SN 0962-9351
YR 2017
FD 2017-01-01
LK http://hdl.handle.net/10668/19055
UL http://hdl.handle.net/10668/19055
LA en
DS RISalud
RD Apr 6, 2025