RT Journal Article T1 Factors associated with successful dietary changes in an energy-reduced Mediterranean diet intervention: a longitudinal analysis in the PREDIMED-Plus trial. A1 Fernandez-Lazaro, Cesar I A1 Toledo, Estefania A1 Buil-Cosiales, Pilar A1 Salas-Salvado, Jordi A1 Corella, Dolores A1 Fito, Montserrat A1 Martinez, J Alfredo A1 Alonso-Gomez, Angel M A1 Wärnberg, Julia A1 Vioque, Jesus A1 Romaguera, Dora A1 Lopez-Miranda, Jose A1 Estruch, Ramon A1 Tinahones, Francisco J A1 Lapetra, Jose A1 Serra-Majem, Luis A1 Bueno-Cavanillas, Aurora A1 Tur, Josep A A1 Martin Sanchez, Vicente A1 Pinto, Xavier A1 Delgado-Rodriguez, Miguel A1 Matia-Martin, Pilar A1 Vidal, Josep A1 Ros, Emilio A1 Vazquez, Clotilde A1 Daimiel, Lidia A1 SanJulian, Beatriz A1 Garcia-Gavilan, Jesus F A1 Sorli, Jose V A1 Castañer, Olga A1 Zulet, M Angeles A1 Tojal-Sierra, Lucas A1 Perez-Farinos, Napoleon A1 Oncina-Canovas, Alejandro A1 Moñino, Manuel A1 Garcia-Rios, Antonio A1 Sacanella, Emilio A1 Bernal-Lopez, Rosa M A1 Santos-Lozano, Jose Manuel A1 Vazquez-Ruiz, Zenaida A1 Muralidharan, Jananee A1 Ortega-Azorin, Carolina A1 Goday, Alberto A1 Razquin, Cristina A1 Goicolea-Güemez, Leire A1 Ruiz-Canela, Miguel A1 Becerra-Tomas, Nerea A1 Schröder, Helmut A1 Martinez Gonzalez, Miguel A K1 Dietary adherence K1 Dietary change K1 Factors K1 Mediterranean diet K1 PREDIMED-Plus K1 Randomized controlled trials AB Long-term nutrition trials may fail to respond to their original hypotheses if participants do not comply with the intended dietary intervention. We aimed to identify baseline factors associated with successful dietary changes towards an energy-reduced Mediterranean diet (MedDiet) in the PREDIMED-Plus randomized trial. Longitudinal analysis of 2985 participants (Spanish overweight/obese older adults with metabolic syndrome) randomized to the active intervention arm of the PREDIMED-Plus trial. Dietary changes were assessed with a 17-item energy-reduced MedDiet questionnaire after 6 and 12 months of follow-up. Successful compliance was defined as dietary changes from baseline of ≥ 5 points for participants with baseline scores  Consistent factors independently associated with successful dietary change at both 6 and 12 months were high baseline perceived self-efficacy in modifying diet (OR6-month: 1.51, 95% CI 1.25-1.83; OR12-month: 1.66, 95% CI 1.37-2.01), higher baseline fiber intake (OR6-month: 1.62, 95% CI 1.07-2.46; OR12-month: 1.62, 95% CI 1.07-2.45), having > 3 chronic conditions (OR6-month: 0.65, 95% CI 0.53-0.79; OR12-month: 0.76, 95% CI 0.62-0.93), and suffering depression (OR6-month: 0.80, 95% CI 0.64-0.99; OR12-month: 0.71, 95% CI 0.57-0.88). Our results suggested that recruitment of individuals with high perceived self-efficacy to dietary change, and those who initially follow diets relatively richer in fiber may lead to greater changes in nutritional recommendations. Participants with multiple chronic conditions, specifically depression, should receive specific tailored interventions. PB Springer YR 2021 FD 2021-10-01 LK http://hdl.handle.net/10668/19875 UL http://hdl.handle.net/10668/19875 LA en NO Fernandez-Lazaro CI, Toledo E, Buil-Cosiales P, Salas-Salvadó J, Corella D, Fitó M, et al. Factors associated with successful dietary changes in an energy-reduced Mediterranean diet intervention: a longitudinal analysis in the PREDIMED-Plus trial. Eur J Nutr. 2022 Apr;61(3):1457-1475 DS RISalud RD Apr 20, 2025